ArticlePituitary2015
Pituicytomas and spindle cell oncocytomas: modern case series from the University of California, San Francisco.
Article in Pituitary, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
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Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Risk factors for tumor recurrence and progression of spindle cell oncocytoma of the pituitary gland: a systematic review and pooled analysis.Pituitary · 2021Pooled it
- Single-fraction stereotactic radiosurgery for spindle cell oncocytoma: preliminary experience and systematic review of the literature.Journal of neuro-oncology · 2019Pooled it
- Primary tumors of the posterior pituitary: A systematic review.Reviews in endocrine & metabolic disorders · 2019Pooled it
- A third ventricular floor-associated TTF-1-positive posterior pituitary tumor: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Case Report: Rare collision tumors: ACTH-secreting pituitary neuroendocrine tumor and pituicytoma - histopathological and ultrastructural analysis.Frontiers in endocrinology · 2026Article
- Pituitary Spindle Cell Oncocytoma: More than a Grade 1 Tumor?Neurology international · 2025Article
- Posterior transpetrosal approach to a suprasellar retroinfundibular pituicytoma: A case report and comprehensive literature review.Brain & spine · 2025Article
- Surgical approach to the treatment of pituicytoma. Report of five cases and a literature review.World neurosurgery: X · 2023Article
- Surgical management of pituicytomas: a single-center case series.Acta neurologica Belgica · 2023Article
- Synchronous Posterior and Anterior Pituitary Tumors: A Case Report of a Hypothetic Paracrine Relationship.Asian journal of neurosurgery · 2023Article
- Pituicytoma: A rare tumor of the sella. A case report and review of literature for diagnosis and management.Surgical neurology international · 2023Article
- Pituitary spindle cell oncocytoma: illustrative case.Journal of neurosurgery. Case lessons · 2021Article
- A Rare Case of Pituicytoma Presenting Cystic Formation.Brain tumor research and treatment · 2021Article
- Clinical features, radiological profiles, pathological features and surgical outcomes of pituicytomas: a report of 11 cases and a pooled analysis of individual patient data.Military Medical Research · 2021Article
- Posterior pituitary tumours: patient outcomes and determinants of disease recurrence or persistence.Endocrine connections · 2021Article
- A rare case of pituicytoma presenting with severe Cushing disease: A case report and review of literature.Medicine · 2019Review
- Spindle cell oncocytoma of the pituitary gland.Journal of neurosurgery · 2019Review
- Histologic, immunohistochemical, and molecular features of pituicytomas and atypical pituicytomas.Acta neuropathologica communications · 2019Article
- Clinical features, diagnosis and therapy of pituicytoma: an update.Journal of endocrinological investigation · 2019Review
- Posterior pituitary tumours: the spectrum of a unique entity. A clinical and histological study of a large case series.Endocrine · 2019Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePituicytomas and spindle cell oncocytomas (SCOs) are extremely rare neoplasms of the sellar and suprasellar region that can often mimic pituitary adenomas. To date, there are relatively few cases of pituicytomas and SCOs reported; and most of these are small case series.
methodsIn this paper, we provide a retrospective review of the treatment, imaging characteristics, post-operative course, and histopathology of five cases of pituicytomas and two SCOs treated at the University of California, San Francisco (UCSF) over a 10-year period from 2003 to 2013.
resultsWe find that pituicytomas and SCOs present similarly to pituitary adenomas, and look identical on CT or MR imaging. We histopathologically confirmed all pituicytomas with a combination of hematoxylin and eosin morphology and immunohistochemical positivity for vimentin and S100; SCOs stain for anti-mitochondrial antigen and endothelial membrane antigen. We observe positive thyroid transcription factor 1 (TTF1) immunohistochemistry in both cases of SCO, as well as in both of the cases of pituicytoma in which TTF1 staining was available.
conclusionsThis represents the largest single-institution case series of pituicytomas and SCOs to date, and also includes the first description of the management of a pregnant female with SCO. Our findings are consistent with the idea of common histogenesis for pituicytomas and SCOs, and also raise the possibility of more aggressive growth in SCOs as compared to pituicytomas.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.