ArticleJournal of the American Geriatrics Society2014
Depression and all-cause mortality in persons with diabetes mellitus: are older adults at higher risk? Results from the Translating Research Into Action for Diabetes Study.
Article in Journal of the American Geriatrics Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Depression and Anxiety as Risk Factors for Morbidity and Mortality After Organ Transplantation: A Systematic Review and Meta-Analysis.Transplantation · 2015Pooled it
- [Geriatric aspects of diabetes mellitus (Update 2026)].Wiener klinische Wochenschrift · 2026Review
- Ethnic Differences in the Prevalence of Mental Health Disorders Among Individuals with Diabetes: A Systematic Review and Meta-analysis.Journal of racial and ethnic health disparities · 2025Article
- Association Between Muscle Quality and Quantitative Changes According to Nutritional Intake Differences in Patients Recovering From Trauma.Clinical nutrition research · 2025Article
- Patterns and determinants of medication adherence among older adult patients with diabetes in Korea: insights from a nationwide survey.BMC geriatrics · 2025Article
- Molecular hallmarks of long non-coding RNAs in aging and its significant effect on aging-associated diseases.Neural regeneration research · 2023Review
- Prior Diagnosis of Diabetes but Not Its Control is Associated with Higher Depression Score Among Older Individuals.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- [Geriatric aspects for the management of diabetes mellitus (Update 2023)].Wiener klinische Wochenschrift · 2023Article
- Association between depressive symptoms and diagnosis of diabetes and its complications: A network analysis in electronic health records.Frontiers in psychiatry · 2022Article
- Four-year changes in central fatness, risk of diabetes, and metabolic control in older adults: a cohort study with mediation analysis.The Korean journal of internal medicine · 2022Article
- Cardiovascular and metabolic morbidity following spinal cord injury.The spine journal : official journal of the North American Spine Society · 2021Article
- Excess mortality in depressive and anxiety disorders: The Lifelines Cohort Study.European psychiatry : the journal of the Association of European Psychiatrists · 2021Article
- High Prevalence of Depressive Symptoms in Patients With Type 1 and Type 2 Diabetes in Developing Countries: Results From the International Diabetes Management Practices Study.Diabetes care · 2021Article
- Association between mental health comorbidity and health outcomes in type 2 diabetes mellitus patients.Scientific reports · 2020Article
- Novel Challenges in Aging with Type 1 Diabetes.Current diabetes reports · 2020Review
- Reducing the Burden of Mortality in Older People With Diabetes: A Review of Current Research.Frontiers in endocrinology · 2020Review
- Gender Differences between Multimorbidity and All-Cause Mortality among Older Adults.Current gerontology and geriatrics research · 2020Article
- Prevalence of type 2 diabetes and their complications among home health care patients at Al-Kharj military industries corporation hospital.Journal of family medicine and primary care · 2019Article
- Patient and Health Care Factors Associated With Long-term Diabetes Complications Among Adults With and Without Mental Health and Substance Use Disorders.JAMA network open · 2019Article
- Adherence to Medication, Physical Activity and Diet in Older Adults With Diabetes: Its Association With Cognition, Anxiety and Depression.Journal of clinical medicine research · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
objectivesTo compare the strength of the association between depression and mortality between elderly and younger individuals with diabetes mellitus.
designA survival analysis conducted in a longitudinal cohort study of persons with diabetes mellitus to test the association between depression and mortality in older (≥ 65) and younger (18-65) adults.
settingManaged care.
participantsPersons aged 18 and older with diabetes mellitus who participated in the Wave 2 survey of the Translating Research Into Action for Diabetes (TRIAD) Study (N = 3,341). MEASUREMENTS: The primary outcome was mortality risk, which was measured as days until death using linked data from the National Death Index. Depression was measured using the Patient Health Questionnaire.
resultsAfter controlling for age, sex, race and ethnicity, income, and other comorbidities, mortality risk in persons with diabetes mellitus was 49% higher in those with depression than in those without, although results varied according to age. After controlling for the same variables, mortality risk in persons aged 65 and older with depression was 78% greater than in those without. For those younger than 65, the effect of depression on mortality was smaller and not statistically significant.
conclusionThis analysis suggests that the effect of depression on mortality in persons with diabetes mellitus is most significant for older adults. Because there is evidence in the literature that treatment of depression in elderly adults can lead to lower mortality, these results may suggest that older adults with diabetes mellitus should be considered a high-priority population for depression screening and treatment.
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Registered trials
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