Evidence map›Paper›PMID 24821533›Full record

ReviewNeuropsychology review2014

Functional plasticity in childhood brain disorders: when, what, how, and whom to assess.

Maureen Dennis, Brenda J Spiegler, Nevena Simic, Katia J Sinopoli, Amy Wilkinson, Keith Owen Yeates, H Gerry Taylor, Erin D Bigler, Jack M Fletcher

Abstract readReview
In one paragraph

Review in Neuropsychology review, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Implications of age at lesion onset for neuropsychological outcomes: A systematic review focusing on focal brain lesions.Cortex; a journal devoted to the study of the nervous system and behavior · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maureen DennisDepartment of Psychology, Program in Neurosciences and Mental Health, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada, maureen.dennis@sickkids.ca.
Brenda J Spiegler
Nevena Simic
Katia J Sinopoli
Amy Wilkinson
Keith Owen Yeates
H Gerry Taylor
Erin D Bigler
Jack M Fletcher

Funding

SUBJECT RECRUITMENT AND EVALUATION COREP01HD035946 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FLETCHER, JACK M · 1998 to 2009
$10.8M
NICHD NIH HHS 1R01 HD04946NICHD NIH HHS P01 HD035946NICHD NIH HHS P01 HD35946NICHD NIH HHS P01 HD35946-06
6 · The paper itself

Abstract

At every point in the lifespan, the brain balances malleable processes representing neural plasticity that promote change with homeostatic processes that promote stability. Whether a child develops typically or with brain injury, his or her neural and behavioral outcome is constructed through transactions between plastic and homeostatic processes and the environment. In clinical research with children in whom the developing brain has been malformed or injured, behavioral outcomes provide an index of the result of plasticity, homeostasis, and environmental transactions. When should we assess outcome in relation to age at brain insult, time since brain insult, and age of the child at testing? What should we measure? Functions involving reacting to the past and predicting the future, as well as social-affective skills, are important. How should we assess outcome? Information from performance variability, direct measures and informants, overt and covert measures, and laboratory and ecological measures should be considered. In whom are we assessing outcome? Assessment should be cognizant of individual differences in gene, socio-economic status (SES), parenting, nutrition, and interpersonal supports, which are moderators that interact with other factors influencing functional outcome.

Indexed as

Neuronal PlasticityOutcome and Process Assessment, Health CareAge FactorsBrainBrain DiseasesChildChild DevelopmentHumansNeuropsychological Tests

Identifiers

PMID24821533
PMCPMC4231018

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.