Evidence map›Paper›PMID 24821471›Full record

ArticleAddictive behaviors2014

Attention-deficit/hyperactivity disorder subtypes and substance use and use disorders in NESARC.

Duneesha De Alwis, Michael T Lynskey, Angela M Reiersen, Arpana Agrawal

Open access · greenAbstract read
In one paragraph

Article in Addictive behaviors, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 107 citations in OpenAlex.

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  10. Chronic Cocaine Use and Parkinson's Disease: An Interpretative Model.International journal of environmental research and public health · 2024
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  16. Attention deficit hyperactivity disorder symptoms and cannabis use after one year among students of the i-Share cohort.European psychiatry : the journal of the Association of European Psychiatrists · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Duneesha De AlwisDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO USA.
Michael T LynskeyKings College, Addictions Department, London, UK.
Angela M ReiersenDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO USA.
Arpana AgrawalDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO USA. Electronic address: agrawala@psychiatry.wustl.edu.
Washington University in St. Louis · USKing's College Hospital · GB

Funding

T32 Training Grant in Epidemiology, Services and Prevention ResearchT32DA007313 · NIDA · WASHINGTON UNIVERSITY · PI PRICE, RUMI KATO · 1999 to 2013
$2.9M
CANNABIS AND TOBACCO INVOLVEMENT: A TWIN STUDYR01DA023668 · NIDA · WASHINGTON UNIVERSITY · PI AGRAWAL, ARPANA · 2007 to 2016
$2.5M
DELINEATING THE ROLE OF GENETIC INFLUENCES ON CANNABIS INVOLVEMENTK02DA032573 · NIDA · WASHINGTON UNIVERSITY · PI AGRAWAL, ARPANA · 2012 to 2021
$1.1M
The Intersection of Autism and ADHDK08MH080287 · NIMH · WASHINGTON UNIVERSITY · PI REIERSEN, ANGELA M. · 2008 to 2012
$788k
CHARACTERIZING THE 3-YEAR COURSE OF CANNABIS INVOLVEMENT IN NESARCR03DA025886 · NIDA · WASHINGTON UNIVERSITY · PI AGRAWAL, ARPANA · 2009 to 2010
$152k
NIDA NIH HHS DA23668NIDA NIH HHS DA25886NIDA NIH HHS K02 DA032573NIDA NIH HHS K02DA32573NIDA NIH HHS R01 DA023668NIDA NIH HHS R03 DA025886NIDA NIH HHS T32 DA007313NIDA NIH HHS T32DA007313NIMH NIH HHS K08 MH080287NIMH NIH HHS MH-080287
6 · The paper itself

Abstract

backgroundAttention-deficit/hyperactivity disorder (ADHD) is associated with substance use and substance use disorders (SUD). However, relatively little is known about the relationship between DSM-IV ADHD subtypes and substance use or DSM-IV abuse/dependence in epidemiological samples.

methodsData were obtained from the National Epidemiologic Survey of Alcohol and Related Conditions (NESARC, N = 33,588). Respondents reported on ADHD symptoms (DSM-IV) for the period of time when they were 17 years or younger. Lifetime use and DSM-IV abuse/dependence of alcohol, nicotine, cannabis, cocaine, sedatives, stimulants and heroin/opiates were compared across those with ADHD symptoms but no diagnosis (ADHDsx; N = 17,009), the Combined (ADHD-C; N = 361), Predominantly Inattentive (ADHD-I; N = 325), and the Predominantly Hyperactive-Impulsive (ADHD-HI; N = 279) ADHD subtypes. Taking a more dimensional approach, inattentive and hyperactive-impulsive symptom counts and their associations with substance use and misuse were also examined.

resultsAfter adjustments for conduct disorder, major depressive disorder, any anxiety disorder and other socio-demographic covariates, substance use and SUD were associated with ADHDsx, ADHD-C, ADHD-I and ADHD-HI. Overall, substance use and SUD were more weakly associated with the ADHDsx group compared to the three ADHD diagnostic groups. Statistically significant differences were not evident across the three diagnostic groups. Hyperactive-impulsive symptoms were more consistently associated with substance use and SUD compared to inattentive symptoms.

conclusionsADHD subtypes are consistently associated with substance use and SUD. The relatively stronger association of hyperactive/impulsive symptoms with substance use and abuse/dependence is consistent with the extant literature noting impulsivity as a precursor of substance use and SUD.

Indexed as

AdolescentAdultAnxiety DisordersAttention Deficit Disorder with HyperactivityConduct DisorderFemaleHumansMajor Depressive DisorderMaleMiddle AgedRetrospective StudiesSelf ReportSubstance-Related DisordersUnited StatesYoung AdultADHD subtypesSubstance useSubstance use disorders

Identifiers

PMID24821471
PMCPMC4135513
OpenAlexW2079335498

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.