ArticleACS applied materials & interfaces2014
Lipid-like self-assembling peptide nanovesicles for drug delivery.
Article in ACS applied materials & interfaces, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 0 citations in OpenAlex.
- Nanovesicle-Based Delivery of Magnesium Chlorophyllin for Photodynamic Inactivation in Agriculture.Small science · 2026Article
- Spontaneous Formation of a Sustainable Antifreeze Coating by Peptide Self-Assembly.ACS applied materials & interfaces · 2025Article
- Exploring How System Dimensions and Periodic Boundary Conditions Influence the Molecular Dynamics Simulation of AThe journal of physical chemistry. B · 2024Article
- Peptide Boronic Acids by Late-Stage Hydroboration on the Solid Phase.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- A novel protein purification scheme based on salt inducible self-assembling peptides.Microbial cell factories · 2023Article
- Structural and photoactive properties of self-assembled peptide-based nanostructures and their optical bioapplication in food analysis.Journal of advanced research · 2023Review
- Multidomain peptide hydrogel adjuvants elicit strong bias towards humoral immunity.Biomaterials science · 2022Article
- Synthetic cells in biomedical applications.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022Review
- Micro- and Nanocapsules Based on Artificial Peptides.Molecules (Basel, Switzerland) · 2022Review
- Supramolecular Self-Assembly of Atomically Precise Silver Nanoclusters with Chiral Peptide for Temperature Sensing and Detection of Arginine.Nanomaterials (Basel, Switzerland) · 2022Article
- Research Progress and Prospects for Polymeric Nanovesicles in Anticancer Drug Delivery.Frontiers in bioengineering and biotechnology · 2022Review
- Peptide-Based Drug Delivery Systems.Medicina (Kaunas, Lithuania) · 2021Review
- Peptide-Assisted Nucleic Acid Delivery Systems on the Rise.International journal of molecular sciences · 2021Review
- High-Loading Self-Assembling Peptide Nanoparticles as a Lipid-Free Carrier for Hydrophobic General Anesthetics.International journal of nanomedicine · 2021Article
- Versatile Types of Polysaccharide-Based Drug Delivery Systems: From Strategic Design to Cancer Therapy.International journal of molecular sciences · 2020Review
- Formulation of pH-Responsive Quatsomes from Quaternary Bicephalic Surfactants and Cholesterol for Enhanced Delivery of Vancomycin against Methicillin ResistantPharmaceutics · 2020Article
- Biomimetic peptide self-assembly for functional materials.Nature reviews. Chemistry · 2020Article
- Self-Assembling Behavior of pH-Responsive Peptide AMolecules (Basel, Switzerland) · 2020Article
- Induced Aggregation of Epoxy Polysiloxane Grafted Gelatin by Organic Solvent and Green Application.Molecules (Basel, Switzerland) · 2019Article
- Anti-EGF antibody cationic polymeric liposomes for delivery of the p53 gene for ovarian carcinoma therapy.International journal of clinical and experimental pathology · 2019Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 3 countries.
Funding
Abstract
Amphiphilic self-assembling peptides are functional materials, which, depending on the amino acid sequence, the peptide length, and the physicochemical conditions, form a variety of nanostructures including nanovesicles, nanotubes, and nanovalves. We designed lipid-like peptides with an aspartic acid or lysine hydrophilic head and a hydrophobic tail composed of six alanines (i.e., ac-A6K-CONH2, KA6-CONH2, ac-A6D-COOH, and DA6-COOH). The resulting novel peptides have a length similar to biological lipids and form nanovesicles at physiological conditions. AFM microscopy and light scattering analyses of the positively charged lipid-like ac-A6K-CONH2, KA6-CONH2 peptide formulations showed individual nanovesicles. The negatively charged ac-A6D-COOH and DA6-COOH peptides self-assembled into nanovesicles that formed clusters that upon drying were organized into necklace-like formations of nanovesicles. Encapsulation of probe molecules and release studies through the peptide bilayer suggest that peptide nanovesicles may be good candidates for sustained release of pharmaceutically active hydrophilic and hydrophobic compounds. Lipid-like peptide nanovesicles represent a paradigm shifting system that may complement liposomes for the delivery of diagnostic and therapeutic agents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.