Evidence map›Paper›PMID 24819475›Full record

ReviewAnnual review of biomedical engineering2014

Computational modeling of cardiac valve function and intervention.

Wei Sun, Caitlin Martin, Thuy Pham

Abstract readReview
In one paragraph

Review in Annual review of biomedical engineering, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. AI-Powered Multimodal Modeling of Personalized Hemodynamics in Aortic Stenosis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Polygonal surface processing and mesh generation tools for the numerical simulation of the cardiac function.International journal for numerical methods in biomedical engineering · 2021
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei SunTissue Mechanics Lab, The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, Georgia 30313; email: wei.sun@bme.gatech.edu.
Caitlin Martin
Thuy Pham

Funding

Probabilistic Modeling of Stenotic Aortic Valve InterventionR01HL104080 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI SUN, WEI · 2011 to 2015
$1.9M
Role of Animal Models in Transcatheter Valve Intervention: A Mechanistic, Age-depR21HL108239 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI SUN, WEI · 2011 to 2012
$414k
Structural Analysis and Comparative Study of Surgical and Transcatheter Valve DevR21HL108240 · NHLBI · UNIVERSITY OF CONNECTICUT STORRS · PI SUN, WEI · 2013 to 2014
$403k
NHLBI NIH HHS R01 HL104080NHLBI NIH HHS R21 HL108239NHLBI NIH HHS R21 HL108240
6 · The paper itself

Abstract

In the past two decades, major advances have been made in the clinical evaluation and treatment of valvular heart disease owing to the advent of noninvasive cardiac imaging modalities. In clinical practice, valvular disease evaluation is typically performed on two-dimensional (2D) images, even though most imaging modalities offer three-dimensional (3D) volumetric, time-resolved data. Such 3D data offer researchers the possibility to reconstruct the 3D geometry of heart valves at a patient-specific level. When these data are integrated with computational models, native heart valve biomechanical function can be investigated, and preoperative planning tools can be developed. In this review, we outline the advances in valve geometry reconstruction, tissue property modeling, and loading and boundary definitions for the purpose of realistic computational structural analysis of cardiac valve function and intervention.

Indexed as

Models, CardiovascularAnimalsAortic ValveBiomechanical PhenomenaComputer SimulationHeart ValvesHumansImaging, Three-DimensionalMitral ValveModels, StatisticalProbabilitySoftwareTissue DistributionTissue Engineeringaortic valvecardiac imagingfinite element analysisheart valvemitral valve

Identifiers

PMID24819475
PMCPMC5481457

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.