Alzheimer neurodegeneration, autophagy, and Abeta secretion: the ins and outs (comment on DOI 10.1002/bies.201400002).

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed.

1. Beyond autophagy: LC3-associated phagocytosis and endocytosis.Science advances · 2022
   Review
2. Amyloid Plaques of Alzheimer's Disease as Hotspots of Glutamatergic Activity.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2019
   Review
3. Neuronal Cell Death.Physiological reviews · 2018
   Review
4. A Novel, Multi-Target Natural Drug Candidate, Matrine, Improves Cognitive Deficits in Alzheimer's Disease Transgenic Mice by Inhibiting Aβ Aggregation and Blocking the RAGE/Aβ Axis.Molecular neurobiology · 2017
   Article
5. Mutations in TrkA Causing Congenital Insensitivity to Pain with Anhidrosis (CIPA) Induce Misfolding, Aggregation, and Mutation-dependent Neurodegeneration by Dysfunction of the Autophagic Flux.The Journal of biological chemistry · 2016
   Article
6. Effects of Ghrelin on the Proteolytic Pathways of Alzheimer's Disease Neuronal Cells.Molecular neurobiology · 2016
   Article
7. Vascular mTOR-dependent mechanisms linking the control of aging to Alzheimer's disease.Biochimica et biophysica acta · 2016
   Review
8. Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments.Frontiers in aging neuroscience · 2016
   Article
9. Suppression of glypican-1 autodegradation by NO-deprivation correlates with nuclear accumulation of amyloid beta in normal fibroblasts.Glycoconjugate journal · 2015
   Article
10. Baclofen mediates neuroprotection on hippocampal CA1 pyramidal cells through the regulation of autophagy under chronic cerebral hypoperfusion.Scientific reports · 2015
    Article
11. Autophagy involving age-related cognitive behavior and hippocampus injury is modulated by different caloric intake in mice.International journal of clinical and experimental medicine · 2015
    Article
12. Autophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex.Neuropsychiatric disease and treatment · 2015
    Article

Corrections and comments

• Comment on
  Dual roles for autophagy: degradation and secretion of Alzheimer's disease Aβ peptide.2014

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

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