Evidence map›Paper›PMID 24819283›Full record

ArticleDermatitis : contact, atopic, occupational, drug

Associations of childhood eczema severity: a US population-based study.

Jonathan I Silverberg, Eric L Simpson

Open access · greenAbstract read
In one paragraph

Article in Dermatitis : contact, atopic, occupational, drug. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
102citing papers in PubMed, 3 pooled it
11.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

102 citing papers in PubMed, 3 syntheses or guidelines pooled it, 253 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT.Health technology assessment (Winchester, England) · 2024
    Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Methotrexate in the treatment of atopic dermatitis.Postepy dermatologii i alergologii · 2025
    Review
  18. Review
  19. Article
  20. Article

42 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jonathan I SilverbergFrom the Departments of *Dermatology, †Preventive Medicine, and ‡Medical Social Sciences, Northwestern University, Chicago, IL; and §Department of Dermatology, Oregon Health and Sciences University, Portland, OR.
Eric L Simpson
Northwestern University · USOregon Health & Science University · US

Funding

The Role of the Skin Barrier in Atopic Dermatitis Development and PreventionK23AR057486 · NIAMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI SIMPSON, ERIC L · 2010 to 2013
$513k
NIAMS NIH HHS K23 AR057486NIAMS NIH HHS K23AR057486
6 · The paper itself

Abstract

backgroundLittle is known about the predictors of eczema severity in the US population.

objectivesWe sought to determine the distribution and associations of childhood eczema severity in the United States.

methodsWe analyzed the data from the 2007 National Survey of Children's Health, a prospective questionnaire-based study of a nationally representative sample of 91,642 children (range, 0-17 years).

resultsThe prevalence of childhood eczema was 12.97% (95% confidence interval [95% CI], 12.42-13.53); 67.0% (95% CI, 64.8-69.2) had mild disease, 26.0% (95% CI, 23.9-28.1) had moderate disease, and 7.0% (95% CI, 5.8-8.3) had severe disease. There was significant statewide variation of the distribution of eczema severity (Rao-Scott χ, P = 0.004), with highest rates of severe disease in Mid-Atlantic and Midwestern states. In univariate models, eczema severity was increased with older age, African American and Hispanic race/ethnicity, lower household income, oldest child in the family, home with a single mother, lower paternal/maternal education level, maternal general health, maternal/paternal emotional health, dilapidated housing, and garbage on the streets. In multivariate survey logistic regression models using stepwise and backward selection, moderate-to-severe eczema was associated with older age, lower household income, and fair or poor maternal health but inversely associated with birthplace outside the United States.

conclusionsThese data indicate that environmental and/or lifestyle factors play an important role in eczema severity.

Indexed as

Population SurveillanceSeverity of Illness IndexAdolescentAge DistributionAsthmaChildChild, PreschoolEczemaFemaleHumansInfantInfant, NewbornMaleOdds RatioPrevalenceRhinitis, Allergic, Seasonal

Identifiers

PMID24819283
PMCPMC4118692
OpenAlexW2060621834

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.