ArticleDermatitis : contact, atopic, occupational, drug
Associations of childhood eczema severity: a US population-based study.
Article in Dermatitis : contact, atopic, occupational, drug. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
102 citing papers in PubMed, 3 syntheses or guidelines pooled it, 253 citations in OpenAlex.
- Effectiveness of Systemic Treatments for Atopic Dermatitis in the Head-and-Neck-Area: A Systematic Review and Meta-analysis.American journal of clinical dermatology · 2026Pooled it
- Systemic Immunomodulatory Treatments for Patients With Atopic Dermatitis: A Systematic Review and Network Meta-analysis.JAMA dermatology · 2020Pooled it
- Association Between Atopic Dermatitis and Suicidality: A Systematic Review and Meta-analysis.JAMA dermatology · 2019Pooled it
- Safety and Tolerability of Ruxolitinib Cream in Adolescents with Mild-to-Moderate Atopic Dermatitis: Results From a 1-Year, Phase III, Open-Label Study.American journal of clinical dermatology · 2026Trial
- Assessing pediatric clinician adherence to the guidelines for prevention of peanut allergy: a natural language processing study.BMC medical informatics and decision making · 2025Trial
- Emollient application from birth to prevent eczema in high-risk children: the BEEP RCT.Health technology assessment (Winchester, England) · 2024Trial
- Safety of Lebrikizumab in Adults and Adolescents with Moderate-to-Severe Atopic Dermatitis: An Integrated Analysis of Eight Clinical Trials.American journal of clinical dermatology · 2023Trial
- Impact of oral abrocitinib on signs, symptoms and quality of life among adolescents with moderate-to-severe atopic dermatitis: an analysis of patient-reported outcomes.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022Trial
- Pharmacokinetics of Ruxolitinib in Patients with Atopic Dermatitis Treated With Ruxolitinib Cream: Data from Phase II and III Studies.American journal of clinical dermatology · 2021Trial
- Efficacy and Safety of Crisaborole Ointment, 2%, for the Treatment of Mild-to-Moderate Atopic Dermatitis Across Racial and Ethnic Groups.American journal of clinical dermatology · 2019Trial
- Minimally invasive skin tape strip RNA sequencing identifies novel characteristics of the type 2-high atopic dermatitis disease endotype.The Journal of allergy and clinical immunology · 2018Trial
- Exploring the effects of visible atopic eczema on willingness for direct and indirect contact.Skin health and disease · 2026Article
- Variations in Healthcare Provider Interactions and Treatment Satisfaction by Patient Race and Ethnicity: A Survey of Adults with Atopic Dermatitis.Advances in therapy · 2026Article
- Use of Ruxolitinib Cream Results in Economic Benefits Compared with Dupilumab in Treatment of Patients with Atopic Dermatitis Meeting Severity Thresholds for Systemic Therapy.Dermatology and therapy · 2026Article
- Characteristics, Disease Burden and Healthcare Resource Use of Moderate and Severe Atopic Dermatitis in Australia.The Australasian journal of dermatology · 2025Article
- Reaching for the Stars in Atopic Dermatitis: Efficacy, Safety, Tolerability, Accessibility, and Remission/Remittive Effects (ESTAR).The Journal of clinical and aesthetic dermatology · 2025Article
- Methotrexate in the treatment of atopic dermatitis.Postepy dermatologii i alergologii · 2025Review
- Moving beyond biology: the critical role of social and structural determinants in atopic dermatitis.International journal of dermatology · 2025Review
- Dietary inflammation: a potential driver of atopic dermatitis?-Evidence from KNHANES 2017-2023.Frontiers in immunology · 2025Article
- Quinolone Use during the First Trimester of Pregnancy and the Risk of Atopic Dermatitis, Asthma, and Allergies of Offspring during 2011 to 2020.Infection & chemotherapy · 2024Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundLittle is known about the predictors of eczema severity in the US population.
objectivesWe sought to determine the distribution and associations of childhood eczema severity in the United States.
methodsWe analyzed the data from the 2007 National Survey of Children's Health, a prospective questionnaire-based study of a nationally representative sample of 91,642 children (range, 0-17 years).
resultsThe prevalence of childhood eczema was 12.97% (95% confidence interval [95% CI], 12.42-13.53); 67.0% (95% CI, 64.8-69.2) had mild disease, 26.0% (95% CI, 23.9-28.1) had moderate disease, and 7.0% (95% CI, 5.8-8.3) had severe disease. There was significant statewide variation of the distribution of eczema severity (Rao-Scott χ, P = 0.004), with highest rates of severe disease in Mid-Atlantic and Midwestern states. In univariate models, eczema severity was increased with older age, African American and Hispanic race/ethnicity, lower household income, oldest child in the family, home with a single mother, lower paternal/maternal education level, maternal general health, maternal/paternal emotional health, dilapidated housing, and garbage on the streets. In multivariate survey logistic regression models using stepwise and backward selection, moderate-to-severe eczema was associated with older age, lower household income, and fair or poor maternal health but inversely associated with birthplace outside the United States.
conclusionsThese data indicate that environmental and/or lifestyle factors play an important role in eczema severity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.