Trial reportDiseases of the colon and rectum2014
Translumbar and transsacral magnetic neurostimulation for the assessment of neuropathy in fecal incontinence.
Trial report in Diseases of the colon and rectum, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Tools for fecal incontinence assessment: lessons for inflammatory bowel disease trials based on a systematic review.United European gastroenterology journal · 2020Pooled it
- Effects of Translumbosacral Neuromodulation Therapy on Gut and Brain Interactions and Anorectal Neuropathy in Fecal Incontinence: A Randomized Study.Neuromodulation : journal of the International Neuromodulation Society · 2021Trial
- A Novel High-Density Electromyography Probe for Evaluating Anorectal Neurophysiology: Design, Human Feasibility Study, and Validation with Trans-Sacral Magnetic Stimulation.Annals of biomedical engineering · 2021Trial
- Comparisons between Manual Lymph Drainage, Abdominal Massage, and Electrical Stimulation on Functional Constipation Outcomes: A Randomized, Controlled Trial.International journal of environmental research and public health · 2020Trial
- Controversies in fecal incontinence.World journal of gastroenterology · 2025Article
- A study of flex miniaturized coils for focal nerve magnetic stimulation.Medical physics · 2023Article
- Short-Term Collagen Nerve Wrapping Facilitates Motor and Sensory Recovery from Nerve Degeneration in a Sciatic Nerve Injury Rat Model.Journal of pain research · 2023Article
- Translumbosacral Anorectal Magnetic Stimulation Test for Fecal Incontinence.Diseases of the colon and rectum · 2022Observational
- Comparative effectiveness of biofeedback and injectable bulking agents for treatment of fecal incontinence: Design and methods.Contemporary clinical trials · 2021Article
- Translumbosacral Neuromodulation Therapy Is a Promising Option for Fecal Incontinence.The American journal of gastroenterology · 2021Article
- Clinical Evaluation of a Patient With Symptoms of Colonic or Anorectal Motility Disorders.Journal of neurogastroenterology and motility · 2020Review
- Epidemiologic Trends and Diagnostic Evaluation of Fecal Incontinence.Gastroenterology & hepatology · 2020Article
- Cortico-anorectal, Spino-anorectal, and Cortico-spinal Nerve Conduction and Locus of Neuronal Injury in Patients With Fecal Incontinence.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019Article
- High-resolution anorectal manometry: An expensive hobby or worth every penny?Neurogastroenterology and motility · 2017Review
- Epidemiology, pathophysiology, and classification of fecal incontinence: state of the science summary for the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) workshop.The American journal of gastroenterology · 2015Article
- Current and emerging treatment options for fecal incontinence.Journal of clinical gastroenterology · 2014Review
- What's New in the Toolbox for Constipation and Fecal Incontinence?Frontiers in medicine · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 5 institutions in 3 countries.
Funding
Abstract
backgroundNeurologic dysfunction causes fecal incontinence, but current techniques for its assessment are limited and controversial.
objectiveThe purpose of this work was to investigate spino-rectal and spino-anal motor-evoked potentials simultaneously using lumbar and sacral magnetic stimulation in subjects with fecal incontinence and healthy subjects and to compare motor-evoked potentials and pudendal nerve terminal motor latency in subjects with fecal incontinence.
designThis was a prospective, observational study. SETTINGS: The study took place in 2 tertiary care centers. PATIENTS: Subjects included adults with fecal incontinence and healthy subjects.
interventionsTranslumbar and transsacral magnetic stimulations were performed bilaterally by applying a magnetic coil to the lumbar and sacral regions in 50 subjects with fecal incontinence (1 or more episodes per week) and 20 healthy subjects. Both motor-evoked potentials and pudendal nerve terminal motor latency were assessed in 30 subjects with fecal incontinence. Stimulation-induced, motor-evoked potentials were recorded simultaneously from the rectum and anus with 2 pairs of bipolar ring electrodes.
main outcome measuresLatency and amplitude of motor-evoked potentials after lumbosacral magnetic stimulation and agreement with pudendal nerve terminal motor latency were measured.
resultsWhen compared with control subjects, 1 or more lumbo-anal, lumbo-rectal, sacro-anal, or sacro-rectal motor-evoked potentials were significantly prolonged (p < 0.01) and were abnormal in 44 (88%) of 50 subjects with fecal incontinence. Positive agreement between abnormal motor-evoked potentials and pudendal nerve terminal motor latency was 63%, whereas negative agreement was 13%. Motor-evoked potentials were abnormal in more (p < 0.05) subjects with fecal incontinence than pudendal nerve terminal motor latency, in 26 (87%) of 30 versus 19 (63%) of 30, and in 24% of subjects with normal pudendal nerve terminal motor latency. There were no adverse events. LIMITATIONS: Anal EMG was not performed.
conclusionsTranslumbar and transsacral magnetic stimulation-induced, motor-evoked potentials provide objective evidence for rectal or anal neuropathy in subjects with fecal incontinence and could be useful. The test was superior to pudendal nerve terminal motor latency and appears to be safe and well tolerated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.