ArticlePloS one2014
Health conditions and their impact among adolescents and young adults with Down syndrome.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03058640 (The Effects of Participation in Karate on Health Outcomes in Adolescents With Down Syndrome), which is not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effects of Participation in Karate on Health Outcomes in Adolescents With Down Syndrome
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Right to Sexuality, Reproductive Health, and Found a Family for People with Intellectual Disability: A Systematic Review.International journal of environmental research and public health · 2023Pooled it
- Effects of 24-week basketball programme on body composition and functional fitness on adults with Down syndrome.Journal of intellectual disability research : JIDR · 2022Trial
- Article
- Cognitive and Behavioural Associations of Visual and Hearing Impairments Across the Lifespan in People With Down Syndrome, a Scoping Review.Journal of intellectual disability research : JIDR · 2025Article
- Accelerometer Output and Oxygen Uptake in Adults With and Without Down Syndrome: METs vs. Percent VOJournal of intellectual disability research : JIDR · 2025Article
- Long-term follow-up of hallux valgus surgery in patients with down's syndrome: a case series.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025Article
- Comprehensive Assessment of Dermatologic and Dysmorphic Manifestations in Patients With Down Syndrome.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024Article
- Down Syndrome and Autoimmune Disease.Clinical reviews in allergy & immunology · 2024Review
- Cardiovascular Complications of Down Syndrome: Scoping Review and Expert Consensus.Circulation · 2023Article
- Article
- Differential expression of cystathionine beta synthase in adolescents with Down syndrome: impact on adiposity.Journal of diabetes and metabolic disorders · 2022Article
- Impact of the COVID-19 pandemic on daily life, mood, and behavior of adults with Down syndrome.Disability and health journal · 2022Article
- Common Dermatologic Disorders in Down Syndrome: Systematic Review.JMIR dermatology · 2022Review
- Care Coordination Needs of Families of Children with Down Syndrome: A Scoping Review to Inform Development of mHealth Applications for Families.Children (Basel, Switzerland) · 2021Article
- Attention Bias and Prodromal Anxiety Symptoms in Toddlers With Fragile X Syndrome and Down Syndrome.American journal on intellectual and developmental disabilities · 2021Article
- Oral Care Experiences and Challenges for Children with Down Syndrome: Reports From Caregivers.Pediatric dentistry · 2020Article
- Three Copies of Four Interferon Receptor Genes Underlie a Mild Type I Interferonopathy in Down Syndrome.Journal of clinical immunology · 2020Article
- Reproducibility of foot dimensions measured from 3-dimensional foot scans in children and adolescents with Down syndrome.Journal of foot and ankle research · 2020Article
- A preliminary examination of brain morphometry in youth with Down syndrome with and without parent-reported sleep difficulties.Research in developmental disabilities · 2020Article
- Early-Onset Noncommunicable Disease and Multimorbidity Among Adults With Pediatric-Onset Disabilities.Mayo Clinic proceedings · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo examine the prevalence of medical conditions and use of health services among young adults with Down syndrome and describe the impact of these conditions upon their lives.
methodsUsing questionnaire data collected in 2011 from parents of young adults with Down syndrome we investigated the medical conditions experienced by their children in the previous 12 months. Univariate, linear and logistic regression analyses were performed.
resultsWe found that in addition to the conditions commonly experienced by children with Down syndrome, including eye and vision problems (affecting 73%), ear and hearing problems (affecting 45%), cardiac (affecting 25%) and respiratory problems (affecting 36%), conditions also found to be prevalent within our young adult cohort included musculoskeletal conditions (affecting 61%), body weight (affecting 57%), skin (affecting 56%) and mental health (affecting 32%) conditions and among young women menstrual conditions (affecting 58%). Few parents reported that these conditions had no impact, with common impacts related to restrictions in opportunities to participate in employment and community leisure activities for the young people, as well as safety concerns.
conclusionThere is the need to monitor, screen and provide appropriate strategies such as through the promotion of healthy lifestyles to prevent the development of comorbidities in young people with Down syndrome and, where present, to reduce their impact.
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