Evidence map›Paper›PMID 24818550›Full record

ArticleGastrointestinal endoscopy2014

Impact of fair bowel preparation quality on adenoma and serrated polyp detection: data from the New Hampshire colonoscopy registry by using a standardized preparation-quality rating.

Joseph C Anderson, Lynn F Butterly, Christina M Robinson, Martha Goodrich, Julia E Weiss

Abstract read
In one paragraph

Article in Gastrointestinal endoscopy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Prevalence of missed lesions in patients with inadequate bowel preparation through a very early repeat colonoscopy.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2022
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  13. Assessing Risk of Index Serrated Polyps.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph C AndersonDepartment of Veterans Affairs Medical Center, White River Junction, Vermont, USA; The Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Lynn F ButterlyThe Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA; Section of Gastroenterology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, USA.
Christina M RobinsonDepartment of Community and Family Medicine, The Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Martha GoodrichDepartment of Community and Family Medicine, The Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.
Julia E WeissDepartment of Community and Family Medicine, The Geisel School of Medicine at Dartmouth, Hanover, New Hampshire, USA.

Funding

Variations in Colonoscopy Screening: A Population Based StudyR01CA131141 · NCI · DARTMOUTH COLLEGE · PI BUTTERLY, LYNN F · 2008 to 2012
$4.5M
NCI NIH HHS R01 CA131141NCI NIH HHS R01CA131141
6 · The paper itself

Abstract

backgroundThe effect of colon preparation quality on adenoma detection rates (ADRs) is unclear, partly because of lack of uniform colon preparation ratings in prior studies. The New Hampshire Colonoscopy Registry collects detailed data from colonoscopies statewide, by using a uniform preparation quality scale after the endoscopist has cleaned the mucosa.

objectiveTo compare the overall and proximal ADR and serrated polyp detection rates (SDR) in colonoscopies with differing levels of colon preparation quality.

designCross-sectional.

settingNew Hampshire statewide registry. PATIENTS: Patients undergoing colonoscopy.

interventionsWe examined colon preparation quality for 13,022 colonoscopies, graded by using specific descriptions provided to endoscopists. ADR and SDR are the number of colonoscopies with at least 1 adenoma or serrated polyp (excluding those in the rectum and/or sigmoid colon) detected divided by the total number of colonoscopies, for the preparation categories: optimal (excellent and/or good), fair, and poor. MAIN OUTCOME MEASUREMENTS: Overall/proximal ADR/SDR.

resultsThe overall detection rates in examinations with fair colon preparation quality (SDR 8.9%; 95% confidence interval [CI], 7.4-10.7, ADR 27.1%; 95% CI, 24.6-30.0) were similar to rates observed in colonoscopies with optimal preparation quality (SDR 8.8%; 95% CI, 8.3-9.4, ADR 26.3%; 95% CI, 25.6-27.2). This finding also was observed for rates in the proximal colon. A logistic regression model (including withdrawal time) found that proximal ADR was statistically lower in the poor preparation category (odds ratio 0.45; 95% CI, 0.24-0.84; P < .01) than in adequately prepared colons. LIMITATIONS: Homogeneous population.

conclusionIn our sample, there was no significant difference in overall or proximal ADR or SDR between colonoscopies with fair versus optimal colon preparation quality. Poor colon preparation quality may reduce the proximal ADR.

Indexed as

RegistriesAdenocarcinomaAdenomaAgedCatharticsCohort StudiesColonic PolypsColonoscopyColorectal NeoplasmsFemaleHumansLogistic ModelsMaleMiddle AgedNew HampshireCathartics

Identifiers

PMID24818550
PMCPMC4134990

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.