ArticleSurgical neurology international2014
Endoscopic endonasal skull base approach for parasellar lesions: Initial experiences, results, efficacy, and complications.
Article in Surgical neurology international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Transclival approaches for intradural pathologies: historical overview and present scenario.Neurosurgical review · 2021Pooled it
- Endoscopic endonasal surgery for cholesteatomas of the posterior cranial fossa and parasellar region. A challenging pathology for experts.Neurosurgical review · 2026Article
- Preoperative Embolization for Tentorial and Subtentorial Tumors.Journal of neuroendovascular therapy · 2026Review
- Endoscopic transnasal resection of clival meningiomas. Analysis of surgical outcomes in 20 patients and literature review.Neurosurgical review · 2025Review
- Not Every Size Fits All: Surgical Corridors for Clival and Cervical Chordomas-A Systematic Review of the Literature and Illustrative Cases.Journal of clinical medicine · 2024Review
- Review
- Surgical complications of endoscopic approach to skull base: analysis of 584 consecutive patients.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022Article
- Article
- An Overview of Managements in Meningiomas.Frontiers in oncology · 2020Review
- The role of multimodal navigation in endoscopic endonasal surgery for giant pituitary adenomas.Gland surgery · 2019Article
- Endoscopic transsphenoidal approach to skull base lesions. A clinical prospective study.Neurosciences (Riyadh, Saudi Arabia) · 2018Article
- Cerebrospinal fluid leaks in extended endoscopic transsphenoidal surgery: covering all the angles.Neurosurgical review · 2017Article
- Endoscopic transsellar approach to pituitary adenomas with cavernous sinus invasion: Is this just a matter of lateral extension?Pituitary · 2016Article
- Langerhans cell histiocytosis causing acute optic neuropathy.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015Article
- Current Status of Endoscopic Endonasal Surgery for Skull Base Meningiomas: Review of the Literature.Neurologia medico-chirurgica · 2015Review
- The cavernous sinus meningiomas' dilemma: Surgery or stereotactic radiosurgery?Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation OncologyReview
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEndoscopic surgery is suitable for the transsphenoidal approach; it is minimally invasive and provides a well-lit operative field. The endoscopic skull base approach through the large opening of the sphenoid sinus through both nostrils has extended the surgical indication for various skull base lesions. In this study, we describe the efficacy and complications associated with the endoscopic skull base approach for extra- or intradural parasellar lesions based on our experiences.
methodsSeventy-four cases were treated by an endoscopic skull base approach. The indications for these procedures included 55 anterior extended approaches, 10 clival approaches, and 9 cavernous approaches. The operations were performed through both the nostrils using a rigid endoscope. After tumor removal, the skull base was reconstructed by a multilayered method using a polyglactin acid (PGA) sheet.
resultsGross total resection was achieved in 82% of pituitary adenomas, 68.8% of meningiomas, and 60% of craniopharyngiomas in anterior extended approach and in 83.3% of chordomas in clival approach, but only in 50% of the tumors in cavernous approach. Tumor consistency, adhesion, and/or extension were significant limitations. Visual function improvements were achieved in 37 of 41 (90.2%) cases. Cerebrospinal fluid (CSF) leakage (9.5%), infections (5.4%), neural injuries (4.1%), and vascular injuries (2.7%) were the major complications.
conclusionsOur experiences show that the endoscopic skull base approach is a safe and effective procedure for various parasellar lesions. Selection of patients who are unlikely to develop complications seems to be an important factor for procedure efficacy and good outcome.
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