Evidence map›Paper›PMID 24817966›Full record

ArticleInternational journal of clinical and experimental pathology2014

SKIP expression is correlated with clinical prognosis in patients with bladder cancer.

Longwang Wang, Mei Zhang, Yong Wu, Cheng Cheng, Yawei Huang, Zimin Shi, Hongwei Huang

Open access · greenAbstract read
In one paragraph

Article in International journal of clinical and experimental pathology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Longwang WangDepartment of Urology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, China.
Mei ZhangDepartment of Neurology, Wuhan Central Hospital Hubei Province, 430014, China.
Yong WuDepartment of Urology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, China.
Cheng ChengDepartment of Urology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, China.
Yawei HuangDepartment of Urology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, China.
Zimin ShiDepartment of Urology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, China.
Hongwei HuangDepartment of Urology, The Second Affiliated Hospital of Nanchang University Nanchang 330006, China.
Nanchang University · CNCentral Hospital of Wuhan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Ski-interacting protein (SKIP) is a transcriptional cofactor distinct from other cofactors and is involved in regulation of many cancer-related proteins. However, its distribution and clinical significances in bladder cancer remains poorly understood. In this study, Quantitative real-time PCR and immunohistochemistry were performed to detect the expression of SKIP in clinical bladder cancer samples. In addition, the correlation of SKIP expression and clinicopathological features and clinical outcomes were analyzed. The expression levels of SKIP in clinical bladder cancer were much higher than that in paired adjacent noncancerous tissues. High expression of SKIP was closely related with histological grades and the poor prognosis of bladder cancer. Based on our data, we speculated that SKIP may be a potential prognostic marker in bladder cancer.

Indexed as

Adaptor Proteins, Signal TransducingAdultAgedBiomarkers, TumorCarcinoma, Transitional CellFemaleGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateMaleMiddle AgedPrognosisRetrospective StudiesRNA, MessengerSurvival RateUrinary BladderAdaptor Proteins, Signal TransducingBiomarkers, TumorRNA, MessengerSPHKAP protein, humanbladder cancerprognosisSKIP expression

Identifiers

PMID24817966
PMCPMC4014250
OpenAlexW2264257780

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.