ArticlePediatric cardiology2014
Transvenous hepatic biopsy in stable Fontan patients undergoing cardiac catheterization.
Article in Pediatric cardiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical predictors and noninvasive imaging in Fontan-associated liver disease: A systematic review and meta-analysis.Hepatology communications · 2024Pooled it
- Fontan-Associated Liver Disease (FALD) in the EUROFontan Experience. An Insight into European Awareness.Pediatric cardiology · 2026Observational
- Unifying FALD assessment-A call to arms.Hepatology communications · 2025Article
- Strain elastography for detecting advanced Fontan-associated liver disease: a retrospective study.BMC gastroenterology · 2025Article
- Transfemoral-Transcaval Liver Biopsy (TFTC) and Transjugular Liver Biopsy (TJLB) in Patients with Fontan-Associated Liver Disease (FALD).Cardiovascular and interventional radiology · 2024Article
- Fontan-associated liver disease: the importance of multidisciplinary teamwork in its management.Frontiers in medicine · 2024Review
- Transient liver elastography in the follow-up of Fontan patients: results of a nation wide survey in Germany.Frontiers in pediatrics · 2023Article
- Incidence, Predictors, and Mortality in Patients With Liver Cancer After Fontan Operation.Journal of the American Heart Association · 2021Article
- Platelet count and abdominal dynamic CT are useful in predicting and screening for gastroesophageal varices after Fontan surgery.PloS one · 2021Article
- Associated Factors of Liver Disease After Fontan Operation in Relation to Ultrasound Liver Elastography.Pediatric cardiology · 2020Article
- The Rate of Hepatic Fibrosis Progression in Patients Post-Fontan.Pediatric cardiology · 2020Article
- Routine Surveillance Catheterization is Useful in Guiding Management of Stable Fontan Patients.Pediatric cardiology · 2020Article
- Hepatic Fibrosis Is Universal Following Fontan Operation, and Severity is Associated With Time From Surgery: A Liver Biopsy and Hemodynamic Study.Journal of the American Heart Association · 2017Article
- MELD-XI Scores Correlate with Post-Fontan Hepatic Biopsy Fibrosis Scores.Pediatric cardiology · 2016Article
- An Observation from Liver Biopsies Two Decades Post-Fontan.Pediatric cardiology · 2016Article
- Fontan Outcomes and Pulmonary Blood Flow at Birth.Pediatric cardiology · 2016Observational
- Magnetic Resonance Elastography: A Novel Technique for the Detection of Hepatic Fibrosis and Hepatocellular Carcinoma After the Fontan Operation.Mayo Clinic proceedings · 2015Article
- Fontan hepatic fibrosis and pulmonary vascular development.Pediatric cardiology · 2015Article
- Late Follow-up of Patients Submitted to Total Cavopulmonary Derivation: Clinical Aspects, Reinterventions, and Complications Interfering in Morbidity and Mortality.Brazilian journal of cardiovascular surgeryArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Liver pathology complicates Fontan palliation. Previous reports established that both hepatic sinusoidal and portal fibrosis occur in patients after Fontan procedures. Past studies predominantly included symptomatic patient cohorts. Thus, the authors of this study aimed to characterize hepatic pathology via transvenous hepatic biopsies in 21 asymptomatic patients at the time of elective cardiac catheterization. Seven of these patients (33 %) were accompanied by an interventional procedure. Hepatic biopsies showed evidence of either sinusoidal or portal fibrosis or both in all but one patient. The findings showed a statistically significant (p = 0.005) moderately strong positive correlation between fibrosis scores and time since Fontan surgery. Additionally, no significant correlation was found between fibrosis scores and inferior vena cava pressure, pulmonary vascular resistance, platelet counts, or serum laboratory testing of hepatic function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.