ArticleEuropean child & adolescent psychiatry2015
Formal thought disorder in autism spectrum disorder predicts future symptom severity, but not psychosis prodrome.
Article in European child & adolescent psychiatry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 5 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 5 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Autism Spectrum Disorder and Clinical High Risk for Psychosis: A Systematic Review and Meta-analysis.Journal of autism and developmental disorders · 2022Pooled it
- Autism spectrum disorder and schizophrenia: An updated conceptual review.Autism research : official journal of the International Society for Autism Research · 2022Pooled it
- Psychosis risk screening in different populations using the Prodromal Questionnaire: A systematic review.Early intervention in psychiatry · 2018Pooled it
- Prevalence of Schizophrenia Spectrum Disorders in Average-IQ Adults with Autism Spectrum Disorders: A Meta-analysis.Journal of autism and developmental disorders · 2018Pooled it
- Neural correlates of formal thought disorder: An activation likelihood estimation meta-analysis.Human brain mapping · 2017Pooled it
- Psychometric properties of the PANSS autism severity score (PAUSS) in young peoples at clinical high risk for psychosis: does it really measure autistic features?European archives of psychiatry and clinical neuroscience · 2026Article
- Evaluating the Prodromal Questionnaire-16 for Screening and Prediction of Psychosis in Autistic Adults: Cross-Sectional and Longitudinal Findings From a National Cohort.Schizophrenia bulletin · 2026Article
- Protocol for the development and testing of the schiZotypy Autism Questionnaire (ZAQ) in adults: a new screening tool to discriminate autism spectrum disorder from schizotypal disorder.BMC psychiatry · 2023Article
- Reported autism diagnosis is associated with psychotic-like symptoms in the Adolescent Brain Cognitive Development cohort.European child & adolescent psychiatry · 2022Article
- Formal Thought Disorder and Executive Functioning in Children and Adolescents with Autism Spectrum Disorder: Old Leads and New Avenues.Journal of autism and developmental disorders · 2017Article
- Can RDoC Help Find Order in Thought Disorder?Schizophrenia bulletin · 2017Review
- Severity of Autism Spectrum Disorders: Current Conceptualization, and Transition to DSM-5.Journal of autism and developmental disorders · 2016Article
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Formal thought disorder (FTD) is a disruption in the flow of thought, which is inferred from disorganisation of spoken language. FTD in autism spectrum disorders (ASD) might be a precursor of psychotic disorders or a manifestation of ASD symptom severity. The current longitudinal study is a seven-year follow-up of 91 individuals aged 5-12 years with ASD. We tested (1) whether childhood FTD predicted prodromal symptoms of psychosis in adolescence and (2) whether childhood FTD was associated with greater ASD symptom severity in adolescence. ASD symptom severity was assessed in childhood (T1) and 7 years later (T2), using the autism diagnostic observation schedule (ADOS). At T1, the Kiddie-Formal Thought Disorder Rating Scale (KFTDS) was used to measure symptoms of FTD. At T2, the prodromal questionnaire (PQ) was used to assess prodromal symptoms of psychosis. FTD at T1 did not predict prodromal symptoms of psychosis at T2 in children with ASD. FTD symptoms at T1, namely illogical thinking, predicted ASD symptom severity at T2 and this effect remained significant after controlling for T1 ASD symptom severity. In children with ASD, illogical thinking predicts severity of ASD symptoms in adolescence, but FTD does not predict prodromal symptoms of psychosis.
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Registered trials
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