Evidence map›Paper›PMID 24816939›Full record

ArticleEuropean radiology2014

Quantitative magnetic resonance imaging (MRI) evaluation of cartilage repair after microfracture (MF) treatment for adult unstable osteochondritis dissecans (OCD) in the ankle: correlations with clinical outcome.

Hongyue Tao, Xiliang Shang, Rong Lu, Hong Li, Yinghui Hua, Xiaoyuan Feng, Shuang Chen

Abstract read
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In one paragraph

Article in European radiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Surgical management of chordoma: A systematic review.The journal of spinal cord medicine · 2020
    Pooled it
  2. No superior treatment for primary osteochondral defects of the talus.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018
    Pooled it
  3. Quantitative T2-Mapping and T2BioMed research international · 2018
    Trial
  4. Clinical and MRI outcomes of HA injection following arthroscopic microfracture for osteochondral lesions of the talus.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2016
    Trial
  5. Correlation between functional impairment and quantitative MRI assessment of ankle cartilage in chronic ankle instability.Asia-Pacific journal of sports medicine, arthroscopy, rehabilitation and technology · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. High reported rate of return to play following bone marrow stimulation for osteochondral lesions of the talus.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2019
    Review
  12. Article
  13. CT arthrography visualizes tissue growth of osteochondral defects of the talus after microfracture.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2018
    Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Hongyue TaoDepartment of Radiology, Huashan Hospital, Fudan University, 12 Wulumuqizhong Road, Shanghai, 200040, China.
Xiliang Shang
Rong Lu
Hong Li
Yinghui Hua
Xiaoyuan Feng
Shuang Chen
Huashan Hospital · CNFudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo quantitatively evaluate cartilage repair after microfracture (MF) for ankle osteochondritis dissecans (OCD) using MRI and analyse correlations between MRI and clinical outcome.

methodsForty-eight patients were recruited and underwent MR imaging, including 3D-DESS, T2-mapping and T2-STIR sequences, and completed American Orthopaedic Foot and Ankle Society (AOFAS) scoring. Thickness index, T2 index of repair tissue (RT) and volume of subchondral bone marrow oedema (BME) were calculated. Subjects were divided into two groups: group A (3-12 months post-op), and group B (12-24 months post-op). Student's t test was used to compare the MRI and AOFAS score between two groups and Pearson's correlation coefficient to analyse correlations between them.

resultsThickness index and AOFAS score of group B were higher than group A (P < 0.001, P < 0.001). T2 index and BME of group B were lower than group A (P < 0.001, P = 0.012). Thickness index, T2 index and BME were all correlated with AOFAS score (r = 0.416, r = -0.475, r = -0.353), but BME was correlated with neither thickness index nor T2 index.

conclusionsSignificant improvement from MF can be expected on the basis of the outcomes of quantitative MRI and AOFAS score. MRI was correlated with AOFAS score. BME is insufficient as an independent predictor to evaluate repair quality, but reduction of BME can improve the patient's clinical outcome. KEY POINTS: • Patients with unstable ankle OCD had satisfactory clinical outcome after MF. • Quantitative MRI correlates with clinical outcome after MF for ankle OCD. • The reduction of subchondral BME will improve the patient's clinical outcome. • Quantitative MRI can monitor the process of cartilage repair over time.

Indexed as

AdolescentAdultAnkle FracturesAnkle JointArthroscopyBone TransplantationCartilage, ArticularFemaleFollow-Up StudiesFracture FixationFractures, SpontaneousHumansMagnetic Resonance ImagingMaleMiddle AgedOsteochondritis Dissecans

Identifiers

PMID24816939
OpenAlexW2151710873

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.