ArticlePloS one2014
Genome-wide transcriptome analysis reveals that cadmium stress signaling controls the expression of genes in drought stress signal pathways in rice.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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52 citing papers in PubMed, 125 citations in OpenAlex.
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- All roads lead to Rome: integrated physiological and transcriptomic analysis of cacao drought response reveals different ways to achieve tolerance in two hybrid clones.Frontiers in plant science · 2026Article
- Intertwining of Cellular Osmotic Stress Handling Mechanisms and Heavy Metal Accumulation.Molecular biotechnology · 2025Review
- Genome-wide identification of potassium transporters and channels in Malus domestica genome.Scientific reports · 2025Article
- Transcriptome Profiles Reveal Key Regulatory Networks during Single and Multifactorial Stresses Coupled with Melatonin Treatment in Pitaya (International journal of molecular sciences · 2024Article
- Comparative transcriptome analysis between two different cadmium-accumulating genotypes of soybean (Glycine max) in response to cadmium stress.BMC genomic data · 2024Article
- Expression of OsHARBI1-1 enhances the tolerance of Arabidopsis thaliana to cadmium.BMC plant biology · 2023Article
- Cadmium accumulation regulated by a rice heavy-metal importer is harmful for host plant and leaf bacteria.Journal of advanced research · 2023Article
- Transcriptome and Physio-Biochemical Profiling Reveals Differential Responses of Rice Cultivars at Reproductive-Stage Drought Stress.International journal of molecular sciences · 2023Article
- OsCERK2/OsRLK10, a homolog of OsCERK1, has a potential role for chitin-triggered immunity and arbuscular mycorrhizal symbiosis in rice.Plant biotechnology (Tokyo, Japan) · 2022Article
- Crosstalk and gene expression in microorganisms under metals stress.Archives of microbiology · 2022Review
- DNA methylation and histone modifications induced by abiotic stressors in plants.Genes & genomics · 2022Review
- Transcriptomic Analysis of Cadmium StressedFrontiers in plant science · 2022Article
- Characterization and Expression Analysis ofEvolutionary bioinformatics online · 2022Article
- Article
- Whole-Genome Sequencing of KMR3 andFrontiers in plant science · 2022Article
- Recent advances in physiological and molecular mechanisms of heavy metal accumulation in plants.Environmental science and pollution research international · 2021Review
- Genome-Wide Analysis ofGenes · 2021Article
- Phospholipases C and D and Their Role in Biotic and Abiotic Stresses.Plants (Basel, Switzerland) · 2021Review
- Global insights to drought stress perturbed genes in oat (Plant signaling & behavior · 2021Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant growth is severely affected by toxic concentrations of the non-essential heavy metal cadmium (Cd). Comprehensive transcriptome analysis by RNA-Seq following cadmium exposure is required to further understand plant responses to Cd and facilitate future systems-based analyses of the underlying regulatory networks. In this study, rice plants were hydroponically treated with 50 µM Cd for 24 hours and ∼60,000 expressed transcripts, including transcripts that could not be characterized by microarray-based approaches, were evaluated. Upregulation of various ROS-scavenging enzymes, chelators and metal transporters demonstrated the appropriate expression profiles to Cd exposure. Gene Ontology enrichment analysis of the responsive transcripts indicated the upregulation of many drought stress-related genes under Cd exposure. Further investigation into the expression of drought stress marker genes such as DREB suggested that expression of genes in several drought stress signal pathways was activated under Cd exposure. Furthermore, qRT-PCR analyses of randomly selected Cd-responsive metal transporter transcripts under various metal ion stresses suggested that the expression of Cd-responsive transcripts might be easily affected by other ions. Our transcriptome analysis demonstrated a new transcriptional network linking Cd and drought stresses in rice. Considering our data and that Cd is a non-essential metal, the network underlying Cd stress responses and tolerance, which plants have developed to adapt to other stresses, could help to acclimate to Cd exposure. Our examination of this transcriptional network provides useful information for further studies of the molecular mechanisms of plant adaptation to Cd exposure and the improvement of tolerance in crop species.
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