Evidence map›Paper›PMID 24816774›Full record

SynthesisPloS one2014

Treatment related impairments in arm and shoulder in patients with breast cancer: a systematic review.

Janine T Hidding, Carien H G Beurskens, Philip J van der Wees, Hanneke W M van Laarhoven, Maria W G Nijhuis-van der Sanden

4 registry-linked trialsOpen access · goldAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 140 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
140citing papers in PubMed, 8 pooled it
8.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04233385 nacompletednot on this mapstarted 2020, after this paper: background citation

Pain and Immobility After Breast Cancer Surgery: A Community-Based Randomized Controlled Trial of Myofascial Massage Treatment

TypeinterventionalSponsorMetroHealth Medical CenterRan2020 to 2025Enrolled132ConditionsBreast Cancer, Mastectomy, Lymphedema, Pain, ShoulderArmsMyofascial Massage, Light Touch
NCT04837248 nacompletednot on this mapstarted 2021, after this paper: background citation

Design and Evaluation of the Effects of a Physical Therapy Program With Digital Support in Patients With Breast Cancer Surgery. A Clinical Trial.

TypeinterventionalSponsorFundacion para la Investigacion Biomedica del Hospital Universitario Ramon y CajalRan2021 to 2024Enrolled92ConditionsBreast CancerArmsActive Comparator: Group 1. Conventional treatment, Experimental: Group 2. Experimental treatment.
NCT05297591 unknown statusnot on this mapstarted 2022, after this paper: background citation

Identifying Prognostic Variables for Persistent Upper Limb Dysfunctions After Breast Cancer Treatment: Longitudinal Cohort Study

TypeobservationalSponsorKU LeuvenRan2022 to 2025Enrolled250ConditionsBreast CancerArmsassessment of UL function and prognostic factors
NCT07673939 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Effects of Core-Focused Exercise Training and Kinesiology Taping Combined With Complex Decongestive Physiotherapy on Posture, Pain, Function, and Quality of Life in Women With Breast Cancer-Related Lymphedema

TypeinterventionalSponsorHacettepe UniversityRan2026 to 2027Enrolled46ConditionsBreast Cancer Related LymphedemaArmsComplex Decongestive Therapy, Trunk Focused exercises, Kinesiology taping, Lower extremity exercises, Placebo taping
3 · Its place in the literature

Who cites it

140 citing papers in PubMed, 8 syntheses or guidelines pooled it, 321 citations in OpenAlex.

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  7. Predictors of persistent pain after breast cancer surgery: a systematic review and meta-analysis of observational studies.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2016
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  16. Breast cancer-related lymphedema and its treatment: how big is the financial impact?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
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  19. Is Xbox 360 Kinect-based virtual reality training as effective as standard physiotherapy in patients undergoing breast cancer surgery?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
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  20. Effect of myofascial techniques for treatment of upper limb dysfunctions in breast cancer survivors: randomized controlled trial.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017
    Trial

80 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Janine T HiddingRadboud university medical center, Department of Orthopedics, Section of Physical Therapy, Nijmegen, The Netherlands; Radboud university medical center, Scientific Institute for Quality of Healthcare, Nijmegen, The Netherlands.
Carien H G BeurskensRadboud university medical center, Department of Orthopedics, Section of Physical Therapy, Nijmegen, The Netherlands.
Philip J van der WeesRadboud university medical center, Scientific Institute for Quality of Healthcare, Nijmegen, The Netherlands.
Hanneke W M van LaarhovenAcademic Medical Center, Department of Medical Oncology, University of Amsterdam, Amsterdam, The Netherlands.
Maria W G Nijhuis-van der SandenRadboud university medical center, Scientific Institute for Quality of Healthcare, Nijmegen, The Netherlands.
Radboud University Medical Center · NLAcademic Medical Center · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBreast cancer is the most common type of cancer in women in the developed world. As a result of breast cancer treatment, many patients suffer from serious complaints in their arm and shoulder, leading to limitations in activities of daily living and participation. In this systematic literature review we present an overview of the adverse effects of the integrated breast cancer treatment related to impairment in functions and structures in the upper extremity and upper body and limitations in daily activities. Patients at highest risk were defined. METHODS AND

findingsWe conducted a systematic literature search using the databases of PubMed, Embase, CINAHL and Cochrane from 2000 to October 2012, according to the PRISMA guidelines. Included were studies with patients with stage I-III breast cancer, treated with surgery and additional treatments (radiotherapy, chemotherapy and hormonal therapy). The following health outcomes were extracted: reduced joint mobility, reduced muscle strength, pain, lymphedema and limitations in daily activities. Outcomes were divided in within the first 12 months and >12 months post-operatively. Patients treated with ALND are at the highest risk of developing impairments of the arm and shoulder. Reduced ROM and muscle strength, pain, lymphedema and decreased degree of activities in daily living were reported most frequently in relation to ALND. Lumpectomy was related to a decline in the level of activities of daily living. Radiotherapy and hormonal therapy were the main risk factors for pain.

conclusionsPatients treated with ALND require special attention to detect and consequently address impairments in the arm and shoulder. Patients with pain should be monitored carefully, because pain limits the degree of daily activities. Future research has to describe a complete overview of the medical treatment and analyze outcome in relation to the treatment. Utilization of uniform validated measurement instruments has to be encouraged.

Indexed as

ArmBreast NeoplasmsHumansShoulder

Identifiers

PMID24816774
PMCPMC4016041
OpenAlexW1969979121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.