Evidence map›Paper›PMID 24816721›Full record

ArticlePloS one2014

Serological cross-reactivity between Merkel cell polyomavirus and two closely related chimpanzee polyomaviruses.

Jérôme T J Nicol, Etienne Liais, Romain Potier, Elisa Mazzoni, Mauro Tognon, Pierre Coursaget, Antoine Touzé

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Jérôme T J NicolUniversité François Rabelais, Virologie Immunologie Moléculaires, Tours, France; INRA UMR 1282, Infectiologie et Santé Publique, Tours, France.
Etienne LiaisUniversité François Rabelais, Virologie Immunologie Moléculaires, Tours, France; INRA UMR 1282, Infectiologie et Santé Publique, Tours, France.
Romain PotierAssociation Beauval Nature pour la Conservation et la Recherche, Saint Aignan sur Cher, France.
Elisa MazzoniDepartment of Morphology, Surgery and Experimental Medicine, School of Medicine, University of Ferrara, Ferrara, Italy.
Mauro TognonDepartment of Morphology, Surgery and Experimental Medicine, School of Medicine, University of Ferrara, Ferrara, Italy.
Pierre CoursagetUniversité François Rabelais, Virologie Immunologie Moléculaires, Tours, France.
Antoine TouzéUniversité François Rabelais, Virologie Immunologie Moléculaires, Tours, France; INRA UMR 1282, Infectiologie et Santé Publique, Tours, France.
Infectiologie Animale et Santé Publique · FRUniversity of Ferrara · ITAssociation pour l'Utilisation du Rein Artificiel dans la région Lyonnaise · FRUniversité de Tours · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phylogenetic analyses based on the major capsid protein sequence indicate that Merkel cell polyomavirus (MCPyV) and chimpanzee polyomaviruses (PtvPyV1, PtvPyV2), and similarly Trichodysplasia spinulosa-associated polyomavirus (TSPyV) and the orangutan polyomavirus (OraPyV1) are closely related. The existence of cross-reactivity between these polyomaviruses was therefore investigated. The findings indicated serological identity between the two chimpanzee polyomaviruses investigated and a high level of cross-reactivity with Merkel cell polyomavirus. In contrast, cross-reactivity was not observed between TSPyV and OraPyV1. Furthermore, specific antibodies to chimpanzee polyomaviruses were detected in chimpanzee sera by pre-incubation of sera with the different antigens, but not in human sera.

Indexed as

PhylogenyAnimalsCapsid ProteinsCluster AnalysisComputational BiologyCross ReactionsHumansItalyMicroscopy, ElectronPan troglodytesPolyomavirusPolyomavirus InfectionsSeroepidemiologic StudiesVirionCapsid ProteinsVP1 protein, polyomavirus

Identifiers

PMID24816721
PMCPMC4016208
OpenAlexW2039301796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.