Evidence map›Paper›PMID 24816589›Full record

ArticlePloS one2014

Characterization of pore structure in biologically functional poly(2-hydroxyethyl methacrylate)-poly(ethylene glycol) diacrylate (PHEMA-PEGDA).

Amelia Zellander, Chenlin Zhao, Mrignayani Kotecha, Richard Gemeinhart, Melissa Wardlow, Jeremiah Abiade, Michael Cho

Abstract read
In one paragraph

Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Amelia ZellanderDepartment of Bioengineering, University of Illinois, Chicago, Illinois, United States of America.
Chenlin ZhaoDepartment of Mechanical and Industrial Engineering, University of Illinois, Chicago, Illinois, United States of America.
Mrignayani KotechaDepartment of Bioengineering, University of Illinois, Chicago, Illinois, United States of America.
Richard GemeinhartDepartment of Biopharmaceutical Sciences, University of Illinois, Chicago, Illinois, United States of America.
Melissa WardlowDepartment of Bioengineering, University of Illinois, Chicago, Illinois, United States of America.
Jeremiah AbiadeDepartment of Mechanical and Industrial Engineering, University of Illinois, Chicago, Illinois, United States of America.
Michael ChoDepartment of Bioengineering, University of Illinois, Chicago, Illinois, United States of America.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A copolymer composed of poly(2-hydroxyethyl methacrylate) (PHEMA) and poly(ethylene glycol) diacrylate (PEGDA) (PHEMA-PEGDA) is structurally versatile. Its structure can be adjusted using the following porogens: water, sucrose, and benzyl alcohol. Using phase separation technique, a variety of surface architectures and pore morphologies were developed by adjusting porogen volume and type. The water and sucrose porogens were effective in creating porous and cytocompatible PHEMA-PEGDA scaffolds. When coated with collagen, the PHEMA-PEGDA scaffolds accommodated cell migration. The PHEMA-PEGDA scaffolds are easy to produce, non-toxic, and mechanically stable enough to resist fracture during routine handling. The PHEMA-PEGDA structures presented in this study may expedite the current research effort to engineer tissue scaffolds that provide both structural stability and biological activity.

Indexed as

Materials TestingBiocompatible MaterialsCollagenFibroblastsHumansPolyethylene GlycolsPolyhydroxyethyl MethacrylatePorosityStress, MechanicalSurface PropertiesBiocompatible MaterialsCollagenpoly(ethylene glycol)diacrylatePolyethylene GlycolsPolyhydroxyethyl Methacrylate

Identifiers

PMID24816589
PMCPMC4016039

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.