ReviewClinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology2015
EEG functional connectivity, axon delays and white matter disease.
Review in Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
50 citing papers in PubMed.
- Evidence for frequency-dependent cortical plasticity in the human brain.Proceedings of the National Academy of Sciences of the United States of America · 2017Trial
- The Relationship Between Resting State Quantitative EEG and Daytime Sleepiness Complaints in Parkinson's Disease.Journal of sleep research · 2026Article
- Clinical utility and prospective of TMS-EEG: Updated review from an international expert group.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2026Review
- The role of white matter myelin in structural-functional network coupling.Communications biology · 2026Article
- Structural integrity of the anterior thalamic radiation predicts alpha oscillations and inattention during visual encoding.Scientific reports · 2026Article
- Silent yet impaired: Hidden memory processing deficits in asymptomatic individuals with moderate-to-severe white matter hyperintensities.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Article
- Article
- White matter microstructural integrity as a key to effective propagation of gamma entrainment in humans.GeroScience · 2025Article
- Interconnected pathways link faecal microbiota plasma lipids and brain activity to childhood malnutrition related cognition.Nature communications · 2025Article
- Neurophysiological Signatures of Major Depressive Disorder and Frontocentral Gamma Auditory Response Deficits.Depression and anxiety · 2025Article
- EEG synchronization patterns during a Go/No-Go task in individuals with aphasia in subacute and chronic phases of stroke.Scientific reports · 2024Article
- Neuronal Coupling Modes Show Differential Development in the Early Cortical Activity Networks of Human Newborns.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Clinical and neuroradiographic features of fentanyl inhalation-induced leukoencephalopathy.BMJ case reports · 2024Article
- Development of the Alpha Rhythm Is Linked to Visual White Matter Pathways and Visual Detection Performance.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Alterations in electroencephalographic functional connectivity in individuals with major depressive disorder: a resting-state electroencephalogram study.Frontiers in neuroscience · 2024Article
- In vivo marker of brainstem myelin is associated to quantitative sleep parameters in healthy young men.Scientific reports · 2023Article
- EEG Correlates of Cognitive Functions in a Child with ASD and White Matter Signal Abnormalities: A Case Report with Two-and-a-Half-Year Follow-Up.Diagnostics (Basel, Switzerland) · 2023Article
- Targeted Modulation of Human Brain Interregional Effective Connectivity With Spike-Timing Dependent Plasticity.Neuromodulation : journal of the International Neuromodulation Society · 2023Article
- Compensatory mechanisms of reduced interhemispheric EEG connectivity during sleep in patients with apnea.Scientific reports · 2023Article
- Cortical amyloid-beta burden is associated with changes in intracortical myelin in cognitively normal older adults.Translational psychiatry · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
objectiveBoth structural and functional brain connectivities are closely linked to white matter disease. We discuss several such links of potential interest to neurologists, neurosurgeons, radiologists, and non-clinical neuroscientists.
methodsTreatment of brains as genuine complex systems suggests major emphasis on the multi-scale nature of brain connectivity and dynamic behavior. Cross-scale interactions of local, regional, and global networks are apparently responsible for much of EEG's oscillatory behaviors. Finite axon propagation speed, often assumed to be infinite in local network models, is central to our conceptual framework.
resultsMyelin controls axon speed, and the synchrony of impulse traffic between distant cortical regions appears to be critical for optimal mental performance and learning. Several experiments suggest that axon conduction speed is plastic, thereby altering the regional and global white matter connections that facilitate binding of remote local networks.
conclusionsCombined EEG and high resolution EEG can provide distinct multi-scale estimates of functional connectivity in both healthy and diseased brains with measures like frequency and phase spectra, covariance, and coherence. SIGNIFICANCE: White matter disease may profoundly disrupt normal EEG coherence patterns, but currently these kinds of studies are rare in scientific labs and essentially missing from clinical environments.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.