Evidence map›Paper›PMID 24815959›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2014

Psychosocial burden and glycemic control during the first 6 years of diabetes: results from the SEARCH for Diabetes in Youth study.

Korey K Hood, Daniel P Beavers, Joyce Yi-Frazier, Ronny Bell, Dana Dabelea, Robert E Mckeown, Jean M Lawrence

Registry-linked trialAbstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05031429 (Time Limited Eating in New-Onset Type 1 Diabetes), which is not on this map. Cited by 91 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05031429 nacompletednot on this mapstarted 2022, after this paper: background citation

Time Limited Eating in New-Onset Type 1 Diabetes: Feasibility, Acceptability, and Effect on β-cell Function

TypeinterventionalSponsorChildren's Hospital Los AngelesRan2022 to 2023Enrolled12ConditionsType 1 DiabetesArmsTime Limited Eating
3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  13. A Randomized Controlled Trial to Prevent Depression and Ameliorate Insulin Resistance in Adolescent Girls at Risk for Type 2 Diabetes.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2016
    Trial
  14. Videoconferencing for Teens With Diabetes: Family Matters.Journal of diabetes science and technology · 2016
    Trial
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  17. [Impact of urban economic level on glycemic control in patients with type 1 diabetes mellitus using doZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026
    Article
  18. Article
  19. A Review of Real-World Evidence About the Use of Automated Insulin Delivery Systems in People With Type 1 Diabetes.Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists · 2025
    Review
  20. Observational

31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Korey K HoodDepartment of Pediatrics, University of California, San Francisco, San Francisco, California. Electronic address: hoodk@peds.ucsf.edu.
Daniel P BeaversDepartment of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Joyce Yi-FrazierDepartment of Pediatrics, University of Washington, Seattle, Washington.
Ronny BellDepartment of Epidemiology and Prevention, Wake Forest School of Medicine, Winston-Salem, North Carolina.
Dana DabeleaDepartment of Epidemiology, Colorado School of Public Health, University of Colorado, Denver, Colorado.
Robert E MckeownDepartment of Epidemiology and Biostatistics, University of South Carolina, Columbia, South Carolina.
Jean M LawrenceDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California.

Funding

Institute of Translational Health SciencesUL1TR000423 · NCATS · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2012 to 2016
$49.4M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
ZIPRASIDONE IN NORMAL HEPATIC FUNCTION SUBJECTS &IN HEPATIC DYSFUCTIN SUBJECTSM01RR000037 · NCRR · UNIVERSITY OF WASHINGTON · PI GIBSON, RONALD L · 1985 to 2007
$33.8M
ZORVIRAX ORAL SUSPENSION FOR SEVERE CHILDHOOD HERPES VIRUS INFECTIONSM01RR000069 · NCRR · UNIVERSITY OF COLORADO DENVER · PI KRUGMAN, RICHARD D. · 1985 to 2008
$22.1M
Colorado Clinical and Translational Science Institute (UL1)UL1TR000154 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2012 to 2013
$20.4M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR026314 · NCRR · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2009 to 2011
$14.3M
UCHSC DIABETES ENDOCRINOLOGY RESEARCH CENTERP30DK057516 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI HUTTON, JOHN C · 2000 to 2010
$14.0M
SOUTH CAROLINA CLINICAL & TRANSLATIONAL RESEARCH INSTITUTE (SCTR)UL1RR029882 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T. · 2009 to 2011
$10.1M
SEARCH for Diabetes in Youth Coordinating CenterU01DP000250 · DP · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI BELL, RONNY A · 2005 to 2009
$4.8M
SEARCH for Diabetes in Youth, Phase 3: Registry Study - Colorado CenterU18DP003256 · DP · UNIVERSITY OF COLORADO DENVER · PI DABELEA, DANA · 2010 to 2014
$3.6M
SEARCH for Diabetes in Youth 2: Colorado CenterU01DP000247 · DP · UNIVERSITY OF COLORADO DENVER · PI DABELEA, DANA · 2005 to 2009
$3.6M
SEARCH for Diabetes in Youth 3: Washington Site, Part BU18DP002710 · DP · SEATTLE CHILDREN'S HOSPITAL · PI PIHOKER, CATHERINE · 2010 to 2014
$3.2M
HSRD VA HIR 10-001NCATS NIH HHS UL1 TR000154NCATS NIH HHS UL1 TR000423NCATS NIH HHS UL1 TR001082NCCDPHP CDC HHS DP-05-069NCCDPHP CDC HHS DP-10-001NCCDPHP CDC HHS U01 DP000244NCCDPHP CDC HHS U01 DP000245NCCDPHP CDC HHS U01 DP000246NCCDPHP CDC HHS U01 DP000247NCCDPHP CDC HHS U01 DP000248NCCDPHP CDC HHS U01 DP000250NCCDPHP CDC HHS U01 DP000254NCCDPHP CDC HHS U18 DP002708NCCDPHP CDC HHS U18 DP002709NCCDPHP CDC HHS U18 DP002710NCCDPHP CDC HHS U18 DP002714NCCDPHP CDC HHS U18 DP003256NCRR NIH HHS 1UL1RR026314-01NCRR NIH HHS M01 RR000037NCRR NIH HHS M01 RR000069NCRR NIH HHS M01RR00037NCRR NIH HHS M01 RR00069NCRR NIH HHS UL1 RR026314NCRR NIH HHS UL1 RR029882NCRR NIH HHS UL1RR029882NIDDK NIH HHS P30 DK057516NIDDK NIH HHS P30 DK57516
6 · The paper itself

Abstract

purposeTo evaluate the psychosocial burden of adolescents with diabetes, determine the trajectory of psychosocial burden, and examine the interdependent relationships between psychosocial burden and glycemic control across the first 6 years of diabetes.

methodsData from SEARCH for Diabetes in Youth, an observational study of U.S. children diagnosed with diabetes before the age of 20, were collected during study visits conducted at baseline and then at 12, 24, and 60 months after baseline. Blood was drawn, clinical and demographic information was collected, and psychosocial burden was evaluated using standardized depression and generic and diabetes-specific health-related quality of life (QOL) surveys.

resultsAmong the 1,307 adolescents (mean age, 14.1±2.5 years) with baseline data, 1,026 had type 1 diabetes and 281 had type 2 diabetes. For those with a 60-month follow-up visit, glycated hemoglobin (A1c) values rose 1.5% from baseline (type 1, 7.7%-9.3% and type 2, 7.3%-8.8%). Adolescents with type 2 diabetes reported more depression and poorer QOL than adolescents with type 1 diabetes. For each diabetes type, there were similar baseline risk factors for higher A1c values: longer diabetes duration, ethnic minority status, and declining diabetes QOL (p < .05). However, youth with type 2 diabetes had higher A1c values with increasing generic QOL, an unexpected finding. Younger adolescents with type 1 diabetes had higher A1c values at the end of the study.

conclusionsSignificant deterioration in glycemic control marks the first 6 years of diabetes for adolescents. Psychosocial burden, particularly poor diabetes-specific QOL, is a contributor to suboptimal glycemic outcomes.

Indexed as

Quality of LifeAdolescentBlood GlucoseDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2FemaleGlycated HemoglobinHumansMaleMinority GroupsBlood GlucoseGlycated HemoglobinAdolescentDepressionGlycemic controlPediatric diabetesPsychosocial burdenQuality of lifeType 1 diabetesType 2 diabetes

Identifiers

PMID24815959
PMCPMC4497539

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.