Evidence map›Paper›PMID 24815073›Full record

ReviewInternational journal of molecular sciences2014

Rationale for the use of upfront whole brain irradiation in patients with brain metastases from breast cancer.

Agnes V Tallet, David Azria, Emilie Le Rhun, Fabrice Barlesi, Antoine F Carpentier, Antony Gonçalves, Sophie Taillibert, Frédéric Dhermain, Jean-Philippe Spano, Philippe Metellus

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Agnes V TalletDepartment of Radiation Oncology, Institut Paoli Calmettes, Marseille 13009, France. talleta@ipc.unicancer.fr.
David AzriaDepartment of Radiation Oncology and INSERM U896, CRLC Val d'Aurelle, Montpellier 34000, France. David.Azria@icm.unicancer.fr.
Emilie Le RhunBreast Unit, Department of Medical Oncology, Oscar Lambret Center, Lille Cedex 59020, France. le_rhun@yahoo.fr.
Fabrice BarlesiMultidisciplinary Oncology and Therapeutic Innovations Department & Centre Investigation Clinique, Aix Marseille University-Assistance Publique Hôpitaux de Marseille, Marseille 13011, France. Fabrice.BARLESI@ap-hm.fr.
Antoine F CarpentierDepartment of Neurology, Hopital Avicenne, Assistance Publique des Hopitaux de Paris, Bobigny 93000, France. antoine.carpentier@avc.aphp.fr.
Antony GonçalvesDepartment of Medical Oncology, Institut Paoli Calmettes, Marseille 13009, France. goncalvesa@ipc.unicancer.fr.
Sophie TaillibertDepartment of Radiation Oncology and Department of Neuro-Oncology, Pitié-Salpétrière Hospital, Paris 75013, France. sophie.taillibert@gmail.com.
Frédéric DhermainDepartment of Radiation Oncology, Institut Gustave Roussy University Hospital, Villejuif 94805, France. Frederic.DHERMAIN@gustaveroussy.fr.
Jean-Philippe SpanoDepartment of Medical Oncology, GH Pitié-Salpêtrière, Université Paris 6, Paris 75013, France. jean-philippe.spano@psl.aphp.fr.
Philippe MetellusDepartment of Radiation Oncology, Institut Paoli Calmettes, Marseille 13009, France. Philippe.METELLUS@ap-hm.fr.
Inserm · FRInstitut Paoli-Calmettes · FRPitié-Salpêtrière Hospital · FRAssistance Publique Hôpitaux de Marseille · FRCentre Oscar Lambret · FRHôpital Avicenne · FRInstitut Gustave Roussy · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the second most common cause of brain metastases and deserves particular attention in relation to current prolonged survival of patients with metastatic disease. Advances in both systemic therapies and brain local treatments (surgery and stereotactic radiosurgery) have led to a reappraisal of brain metastases management. With respect to this, the literature review presented here was conducted in an attempt to collect medical evidence-based data on the use of whole-brain radiotherapy for the treatment of brain metastases from breast cancer. In addition, this study discusses here the potential differences in outcomes between patients with brain metastases from breast cancer and those with brain metastases from other primary malignancies and the potential implications within a treatment strategy.

Indexed as

BrainBrain NeoplasmsBreastBreast NeoplasmsCombined Modality TherapyCranial IrradiationFemaleHumansRadiation-Sensitizing AgentsSurvival AnalysisRadiation-Sensitizing Agents

Identifiers

PMID24815073
PMCPMC4057724
OpenAlexW2127310471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.