Evidence map›Paper›PMID 24815069›Full record

ArticleInternational journal of molecular sciences2014

Microwave assistant synthesis, antifungal activity and DFT theoretical study of some novel 1,2,4-triazole derivatives containing pyridine moiety.

Guo-Xiang Sun, Ming-Yan Yang, Yan-Xia Shi, Zhao-Hui Sun, Xing-Hai Liu, Hong-Ke Wu, Bao-Ju Li, Yong-Gang Zhang

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. First report of Stemphylium lycopersici keratitis, a complex corneal infection case.Journal of ophthalmic inflammation and infection · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guo-Xiang SunSchool of Chemical and Biological Engineering, Yancheng Institute of Technology, Yancheng 224051, China. sunguoxiangyit@gmail.com.
Ming-Yan YangCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China. yangmingyanzjut@126.com.
Yan-Xia ShiInstitute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100014, China. shiyanxia813@163.com.
Zhao-Hui SunCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China. esunzhaohui@126.com.
Xing-Hai LiuCollege of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014, China. xhliu@zjut.edu.cn.
Hong-Ke WuSchool of Chemical and Biological Engineering, Yancheng Institute of Technology, Yancheng 224051, China. wuhk910@gmail.com.
Bao-Ju LiInstitute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100014, China. libj@mail.caas.net.cn.
Yong-Gang ZhangBiology Institute of Shandong Academy of Science, Jinan 250014, China. zhangyg@sdas.org.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to investigate the biological activity of novel 1,2,4-triazole compounds, seventeen novel 1,2,4-triazole derivatives containing pyridine moiety were synthesized under microwave assistant condition by multi-step reactions. The structures were characterized by 1H NMR, MS and elemental analyses. The target compounds were evaluated for their fungicidal activities against Stemphylium lycopersici (Enjoji) Yamamoto, Fusarium oxysporum. sp. cucumebrium, and Botrytis cinerea in vivo, and the results indicated that some of the title compounds displayed excellent fungicidal activities. Theoretical calculation of the title compound was carried out with B3LYP/6-31G (d,p). The full geometry optimization was carried out using 6-31G (d,p) basis set, and the frontier orbital energy, atomic net charges were discussed, and the structure-activity relationship was also studied.

Indexed as

Antifungal AgentsChemistry Techniques, SyntheticFungiHumansMicrowavesModels, MolecularMycosesPyridinesTriazoles1,2,4-triazoleAntifungal AgentspyridinePyridinesTriazoles

Identifiers

PMID24815069
PMCPMC4057720

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.