ArticleCancer science2014
Incidence of multiple primary cancers and interval between first and second primary cancers.
Article in Cancer science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 5 of them syntheses that pooled it.
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Who cites it
47 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Risks of colorectal and extracolonic cancers following colorectal cancer: a systematic review and meta-analysis.JNCI cancer spectrum · 2025Pooled it
- Risks of second non-breast primaries following breast cancer in women: a systematic review and meta-analysis.Breast cancer research : BCR · 2023Pooled it
- Pooled it
- Risk of extracolonic second primary cancers following a primary colorectal cancer: a systematic review and meta-analysis.International journal of colorectal disease · 2022Pooled it
- Risk of second primary cancer among breast cancer patients: A systematic review and meta-analysis.Frontiers in oncology · 2022Pooled it
- Subsequent primary cancer incidence among cancer survivors in the United States, 1975-2019: An age-period-cohort analysis.PLoS medicine · 2026Article
- A clinical report and analysis of metachronous multiple primary cancers occurred in four sites.Journal of cancer research and clinical oncology · 2025Article
- Role of muscle glucometabolism derived fromQuantitative imaging in medicine and surgery · 2025Article
- Risk of Second Primary Neoplasms Among Cancer Survivors: A Population-Based, Cohort Study in Golestan Province, Northern Iran, 2004-2019.Cancer medicine · 2025Article
- The effect of thyroid cancer on the survival of patients with digestive system tumors using SEER database.Scientific reports · 2024Article
- Epidemiology, Pattern, and Survival of Multiple Primary Malignant Neoplasms in Southeast Iran: Results of Kerman Population-Based Cancer Registry 2014-2020.Asian Pacific journal of cancer prevention : APJCP · 2024Article
- Incidence, risk and prognosis of second primary malignancy of patients with gastric adenocarcinoma.Scientific reports · 2024Article
- A pancancer analysis of the clinical and genomic characteristics of multiple primary cancers.Scientific reports · 2024Article
- Characteristics and classification of first primary cancer patients with second primary cancer: a population-based cohort study.Clinical and experimental medicine · 2023Article
- Prognostic impact of the presence or absence of prior cancer in patients with cancer using cure models: A population-based study.Cancer science · 2023Article
- [A case of laryngeal carcinoma complicated with Hodgkin's lymphoma].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023Article
- The epidemiology of multiple primary cancers in Belgium (2004-2017): Incidence, proportion, risk, stage and impact on relative survival estimates.BMC cancer · 2023Article
- Cause of Death among Long-Term Cancer Survivors: The NANDE Study.Healthcare (Basel, Switzerland) · 2023Article
- Risk and prediction of multiple primary malignancies after early gastric cancer.Frontiers in oncology · 2023Article
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this retrospective study, we aimed to clarify the risk of developing a second primary cancer and to determine the periods of high risk of second primary cancers. Subjects were all patients who had been diagnosed with a first primary cancer and registered with the Nagasaki Prefecture Cancer Registry between 1985 and 2007. We calculated the standardized incidence ratio (SIR) of second primary cancer according to site and years after diagnosis of the first primary cancer. A second primary cancer developed in 14 167 of 174 477 subjects (8.1%) during a median follow-up of 1.8 years. The SIR of all cancer was 1.10 (95% confidence interval, 1.08-1.11). Some specific relationships were observed between sites with risk factors in common, such as smoking, drinking, and hormone status. The SIRs were relatively high after approximately 10 years for all sites, and trends differ among cancer sites. We showed that cancer patients are at higher risk of a second primary cancer than the general population. In respect of the risk of a second primary cancer, physicians should be alert for cancers that have risk factors in common with the first primary cancer.
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