ReviewNature reviews. Microbiology2014
The hybrid nature of the Eukaryota and a consilient view of life on Earth.
Review in Nature reviews. Microbiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
66 citing papers in PubMed, 138 citations in OpenAlex.
- Toward a genomic understanding of the tree of life.Molecular biology and evolution · 2026Article
- Insights into the effects of gut microbiota and circulating metabolites on oral cancer: Mendelian randomization analysis and clinical validation.Frontiers in nutrition · 2026Article
- Chimeric origins and dynamic evolution of central carbon metabolism in eukaryotes.Nature ecology & evolution · 2025Article
- A reassessment of the "hard-steps" model for the evolution of intelligent life.Science advances · 2025Review
- Origins and Functional Significance of Eukaryotic Protein Folds.Journal of molecular evolution · 2023Article
- Studying the Human Microbiota: Advances in Understanding the Fundamentals, Origin, and Evolution of Biological Timekeeping.International journal of molecular sciences · 2023Review
- Origin and Early Diversification of the Papain Family of Cysteine Peptidases.International journal of molecular sciences · 2023Article
- Sub-lethal signals in the mitochondrial apoptosis apparatus: pernicious by-product or physiological event?Cell death and differentiation · 2023Review
- Microbes 'R' us.Environmental microbiology · 2023Article
- Article
- A Practical Guide to Design and Assess a Phylogenomic Study.Genome biology and evolution · 2022Article
- Eukaryogenesis and oxygen in Earth history.Nature ecology & evolution · 2022Review
- Looking through the Lens of the Ribosome Biogenesis Evolutionary History: Possible Implications for Archaeal Phylogeny and Eukaryogenesis.Molecular biology and evolution · 2022Article
- The existence of a nonclassical TCA cycle in the nucleus that wires the metabolic-epigenetic circuitry.Signal transduction and targeted therapy · 2021Article
- Tempos and modes of collectivity in the history of life.Theory in biosciences = Theorie in den Biowissenschaften · 2021Review
- The Asgard Archaeal-Unique Contribution to Protein Families of the Eukaryotic Common Ancestor Was 0.3.Genome biology and evolution · 2021Article
- The origin of phagocytosis in Earth history.Interface focus · 2020Review
- The Syntrophy hypothesis for the origin of eukaryotes revisited.Nature microbiology · 2020Review
- Bacterial Genes Outnumber Archaeal Genes in Eukaryotic Genomes.Genome biology and evolution · 2020Article
- Eukaryotes Are a Holophyletic Group of Polyphyletic Origin.Frontiers in microbiology · 2020Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The origin of the eukaryotic cell, which is known as eukaryogenesis, has puzzled scientists for more than 100 years, and many hypotheses have been proposed. Recent analyses of new data enable the safe elimination of some of these hypotheses, whereas support for other hypotheses has increased. In this Opinion article, we evaluate the available theories for their compatibility with empirical observations and conclude that cellular life consists of two primary, paraphyletic prokaryotic groups and one secondary, monophyletic group that has symbiogenic origins - the eukaryotes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.