Evidence map›Paper›PMID 24813550›Full record

ArticleAddictive behaviors2014

The mediating role of depression in the relationship between anxiety sensitivity and alcohol dependence.

William V Lechner, Julia M Shadur, Anne N Banducci, DeMond M Grant, Melanie Morse, C W Lejuez

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Addictive behaviors, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
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  5. Article
  6. Anxiety sensitivity in relation to cigarette smoking and other substance use in African American smokers.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

William V LechnerOklahoma State University, 118 North Murray Hall, Stillwater, OK 74075, United States; Center for Addictions, Personality, and Emotion Research, University of Maryland, College Park, MD 20742, United States. Electronic address: william.lechner@okstate.edu.
Julia M ShadurCenter for Addictions, Personality, and Emotion Research, University of Maryland, College Park, MD 20742, United States.
Anne N BanducciCenter for Addictions, Personality, and Emotion Research, University of Maryland, College Park, MD 20742, United States.
DeMond M GrantOklahoma State University, 118 North Murray Hall, Stillwater, OK 74075, United States.
Melanie MorseCenter for Addictions, Personality, and Emotion Research, University of Maryland, College Park, MD 20742, United States.
C W LejuezCenter for Addictions, Personality, and Emotion Research, University of Maryland, College Park, MD 20742, United States.

Funding

Drug Choice, Impulsivity, and Risky Sexual BehaviorR01DA019405 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI LEJUEZ, CARL W · 2006 to 2009
$1.3M
NIDA NIH HHS R01 DA019405NIDA NIH HHS R01 DA19405
6 · The paper itself

Abstract

backgroundMany studies have reported that Anxiety Sensitivity (AS) is positively associated with alcohol use or other alcohol-related variables. More recent mediator and moderator models have shown promise in elucidating mechanisms within this relationship; the literature to date suggests that the relationship between AS and alcohol is likely mediated by problematic coping motives. However, few studies have considered the effects of depression within the AS-alcohol use relationship, despite a strong body of evidence linking AS to subsequent depression and depression to subsequent alcohol use problems, independently. Therefore, the current study assessed depression as a potential mediator of this relationship.

methodParticipants were 418 sequential admissions to a substance abuse treatment facility. A mediation analysis using bootstrapping was utilized in order to estimate indirect effects of AS on alcohol dependence through depression.

resultsResults reveal an indirect effect suggesting that the effects of anxiety sensitivity on alcohol dependence are mediated by symptoms of depression. More specifically, the effects of AS total score and AS somatic sensations on alcohol dependence were mediated by symptoms of depression. Lastly, a dual mediator model demonstrated that both depression and problematic coping uniquely mediate the relationship between AS and alcohol dependence.

conclusionsWhile preliminary in nature, the current study provides evidence supporting the hypothesis that depression is an important factor to consider when examining the relationship between AS and alcohol dependence.

Indexed as

Adaptation, PsychologicalAdultAlcoholismAnxiety DisordersDepressive DisorderDistrict of ColumbiaFemaleHumansMaleMiddle AgedSelf ReportAlcohol dependenceAnxietyAnxiety sensitivityDepressionMediation

Identifiers

PMID24813550
PMCPMC4071347

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.