ReviewGastroenterology clinics of North America2014
Allergic mechanisms in eosinophilic esophagitis.
Review in Gastroenterology clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Microbiome in Eosinophilic Esophagitis-Metagenomic, Metatranscriptomic, and Metabolomic Changes: A Systematic Review.Frontiers in physiology · 2021Pooled it
- Systematic review: Eosinophilic esophagitis in Asian countries.World journal of gastroenterology · 2015Pooled it
- Latent Variable Indirect Response Modeling of Cendakimab Exposure-Response for Longitudinal Dysphagia Days Using a Combined Uniform-Binomial Likelihood Framework.CPT: pharmacometrics & systems pharmacology · 2026Trial
- Evaluation of the Effect of Cendakimab on the Pharmacokinetics of CYP Probe Drugs in Patients With Eosinophilic Esophagitis.Clinical and translational science · 2026Article
- PSMB8 stratifies therapy response in eosinophilic esophagitis.Clinical and experimental immunology · 2026Article
- Eosinophilic esophagitis in children: A multicenter study evaluating current practices in Mexico.The journal of allergy and clinical immunology. Global · 2025Article
- Expert Recommendations on the Diagnosis of Eosinophilic Esophagitis in the United Arab Emirates.Cureus · 2024Review
- An Autobiographical Case Report of Eosinophilic Esophagitis: A Diagnosis That Is Hard to Swallow.Cureus · 2023Article
- Eosinophilic esophagitis auxiliary diagnosis based on a peptide ligand to eosinophil cationic protein in esophageal mucus of pediatric patients.Scientific reports · 2022Observational
- Examining the Role of Type 2 Inflammation in Eosinophilic Esophagitis.Gastro hep advances · 2022Review
- Clinical spectrum of paediatric and adult eosinophilic oesophagitis in the North East of England from 2016 to 2019.Frontline gastroenterology · 2022Article
- OX40 Expression in Eosinophils Aggravates OVA-Induced Eosinophilic Gastroenteritis.Frontiers in immunology · 2022Article
- Noninvasive biomarkers identify eosinophilic esophagitis: A prospective longitudinal study in children.Allergy · 2021Article
- Conserved IFN Signature between Adult and Pediatric Eosinophilic Esophagitis.Journal of immunology (Baltimore, Md. : 1950) · 2021Observational
- Hypersensitivity Reactions: An Everyday Occurrence in Pediatric Allergy Clinics.Pediatric allergy, immunology, and pulmonology · 2020Review
- The Role of Food Allergy in Eosinophilic Esophagitis.Journal of asthma and allergy · 2020Review
- Signals from the various immune cells in promoting food allergy-induced eosinophilic esophagitis like disease.Asia Pacific allergy · 2019Review
- The Salivary Microbiome Is Altered in Children With Eosinophilic Esophagitis and Correlates With Disease Activity.Clinical and translational gastroenterology · 2019Article
- Changing Concept of the Prevalence of Eosinophilic Esophagitis: Visible and Hidden Patients.Clinical endoscopy · 2018Article
- Biological therapies for eosinophilic gastrointestinal diseases.The Journal of allergy and clinical immunology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Eosinophilic esophagitis is rapidly increasing in incidence. It is associated with food antigen-triggered, eosinophil-predominant inflammation, and the pathogenic mechanisms have many similarities to other chronic atopic diseases. Studies in animal models and from patients have suggested that allergic sensitization leads to food-specific IgE and T-helper lymphocyte type 2 cells, both of which seem to contribute to the pathogenesis along with basophils, mast cells, and antigen-presenting cells. In this review our current understandings of the allergic mechanisms that drive eosinophilic esophagitis are outlined, drawing from clinical and translational studies in humans as well as experimental animal models.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.