ArticleGastroenterology clinics of North America2014
Eosinophilic esophagitis: interactions with gastroesophageal reflux disease.
Article in Gastroenterology clinics of North America, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
31 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Eosinophilic esophagitis in children and adolescents: a clinical practice guideline.Italian journal of pediatrics · 2025Guideline
- Guideline
- Peripheral T-cell transitions following proton pump inhibitor therapy in eosinophilic esophagitis.Clinical and experimental immunology · 2026Article
- Eosinophilic and mastocytic gastrointestinal diseases: current knowledge and controversy in histopathologic diagnosis.Translational gastroenterology and hepatology · 2026Review
- Eosinophilic esophagitis in children: A multicenter study evaluating current practices in Mexico.The journal of allergy and clinical immunology. Global · 2025Article
- Suprabasal cells retain progenitor cell identity programs in eosinophilic esophagitis-driven basal cell hyperplasia.JCI insight · 2023Article
- Suprabasal cells retaining stem cell identity programs drive basal cell hyperplasia in eosinophilic esophagitis.bioRxiv : the preprint server for biology · 2023Article
- A case of eosinophilic esophagitis with autoimmune polyendocrine syndrome type 2, including autoimmune gastritis.Clinical journal of gastroenterology · 2021Article
- Identification of Unique Transcriptomic Signatures and Hub Genes Through RNA Sequencing and Integrated WGCNA and PPI Network Analysis in Nonerosive Reflux Disease.Journal of inflammation research · 2021Article
- Validation of the diagnosis of eosinophilic esophagitis based on histopathology reports in Sweden.Upsala journal of medical sciences · 2021Article
- Malnutrition in Eosinophilic Gastrointestinal Disorders.Nutrients · 2020Review
- Early Life Risk Factors in Pediatric EoE: Could We Prevent This Modern Disease?Frontiers in pediatrics · 2020Review
- Eosinophilic esophagitis after total gastrectomy treated with proton pump inhibitors: a case report.Clinical journal of gastroenterology · 2019Article
- Obesity and hiatal hernia may be non-allergic risk factors for esophageal eosinophilia in Japanese adults.Esophagus : official journal of the Japan Esophageal Society · 2019Article
- Gastroesophageal Reflux Disease and Eosinophilic Esophagitis.Gastroenterology & hepatology · 2019Article
- Eosinophilic esophagitis incidence in New Zealand: high but not increasing.Clinical and experimental gastroenterology · 2019Article
- Eosinophilic esophagitis: pathophysiology and its clinical implications.American journal of physiology. Gastrointestinal and liver physiology · 2018Review
- Gastro-oesophageal reflux disease and eosinophilic oesophagitis: What is the relationship?World journal of gastrointestinal pathophysiology · 2018Review
- Review
- Diagnostic Trends and Clinical Characteristics of Eosinophilic Esophagitis: A Korean, Single-center Database Study.Journal of neurogastroenterology and motility · 2018Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Gastroesophageal reflux disease (GERD) and eosinophilic esophagitis (EoE) are not mutually exclusive. The notion that GERD and EoE can be distinguished by the response to proton pump inhibitor (PPI) treatment is based on the mistaken assumption that gastric acid suppression is the only important therapeutic effect of PPIs, and therefore only GERD can respond to PPIs. We believe that a clinical or histologic response to PPIs does not rule in GERD or rule out EoE. We recommend a trial of PPI therapy for patients with symptomatic esophageal eosinophilia, even if the diagnosis of EoE seems clear-cut.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.