Evidence map›Paper›PMID 24813302›Full record

ArticleJournal of the American Academy of Dermatology2014

Guidelines of care for the management of atopic dermatitis: section 2. Management and treatment of atopic dermatitis with topical therapies.

Lawrence F Eichenfield, Wynnis L Tom, Timothy G Berger, Alfons Krol, Amy S Paller, Kathryn Schwarzenberger, James N Bergman, Sarah L Chamlin, David E Cohen, Kevin D Cooper and 13 more

5 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in Journal of the American Academy of Dermatology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 5 registered trials, which are not on this map. Cited by 425 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
425citing papers in PubMed, 10 pooled it
73.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02763722 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Evaluating Results of Regularly Applied Emollient - Spray in Atopic Dermatitis Therapy

TypeinterventionalSponsorMedical University of WarsawRan2016 to 2016Enrolled35ConditionsAtopic DermatitisArmsEmollient spray product
NCT02864498 phase2completednot on this mapstarted 2017, after this paper: background citation

A Randomised, Double-blind, Placebo-controlled, Phase 2b Study to Assess the Efficacy and Safety of Orally Administered DS107 in Patients With Moderate to Severe Atopic Dermatitis

TypeinterventionalSponsorDS BiopharmaRan2017 to 2018Enrolled321ConditionsAtopic DermatitisArmsDS107, Placebo
NCT03775590 naterminatednot on this mapstarted 2019, after this paper: background citation

The Role of Bathing Additives in the Treatment of Pediatric Atopic Dermatitis

TypeinterventionalSponsorMayo ClinicRan2019 to 2019Enrolled5ConditionsAtopic Dermatitis, EczemaArmsWater, Bleach, Acetic acid
NCT03832010 phase4completednot on this mapstarted 2019, after this paper: background citation

Proof of Concept Investigation of the Steroid-reducing Effects of Crisaborole in Children

TypeinterventionalSponsorJohns Hopkins UniversityRan2019 to 2024Enrolled24ConditionsAtopic Dermatitis, EczemaArmsCrisaborole, Hydrocortisone Ointment, Triamcinolone ointment, Aquaphor
NCT06980961 narecruitingnot on this mapstarted 2025, after this paper: background citation

Short-pulse and Ultra-Short Pulse ND: YAG 1064 Lasers for Stasis Dermatitis Secondary to Chronic Venous Hypertension Treatment: the SUPERSTAR Trial

TypeinterventionalSponsorScience Valley Research InstituteRan2025 to 2026Enrolled20ConditionsStasis DermatitisArmsshort-pulse ND: YAG 1064 laser, ultra-short-pulse ND: YAG 1064 laser, cold cream
3 · Its place in the literature

Who cites it

425 citing papers in PubMed, 10 syntheses or guidelines pooled it, 1,176 citations in OpenAlex.

  1. Skin barrier-related genes in childhood atopic dermatitis, asthma, and allergy: A systematic review and meta-analysis.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Topical anti-inflammatory treatments for eczema: network meta-analysis.The Cochrane database of systematic reviews · 2024
    Pooled it
  9. Guideline
  10. Skin care interventions in infants for preventing eczema and food allergy.The Cochrane database of systematic reviews · 2022
    Pooled it
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Rapid pruritus reduction with ruxolitinib cream treatment in patients with atopic dermatitis.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023
    Trial
  16. Trial
  17. Monoclonal Antibodies in Pediatric Atopic Dermatitis; Efficacy and Safety.Current therapeutic research, clinical and experimental · 2026
    Review
  18. Review
  19. Review
  20. Article

365 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 17 institutions in 4 countries.

Lawrence F EichenfieldDivision of Pediatric and Adolescent Dermatology, University of California, San Diego, California; Rady Children's Hospital, San Diego, California.
Wynnis L TomDivision of Pediatric and Adolescent Dermatology, University of California, San Diego, California; Rady Children's Hospital, San Diego, California.
Timothy G BergerDepartment of Dermatology, University of California, San Francisco, California.
Alfons KrolDepartment of Dermatology, Oregon Health and Science University, Portland, Oregon.
Amy S PallerDepartment of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Kathryn SchwarzenbergerKaplan-Amonette Department of Dermatology, University of Tennessee Health Science Center, Memphis, Tennessee.
James N BergmanDepartment of Dermatology and Skin Science, University of British Columbia, Vancouver, British Columbia, Canada.
Sarah L ChamlinDepartment of Dermatology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois.
David E CohenRonald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.
Kevin D CooperDepartment of Dermatology, Case Western University, Cleveland, Ohio.
Kelly M CordoroDepartment of Dermatology, University of California, San Francisco, California.
Dawn M DavisDepartment of Dermatology, Mayo Clinic, Rochester, Minnesota.
Steven R FeldmanDepartment of Dermatology, Wake Forest University Health Sciences, Winston-Salem, North Carolina.
Jon M HanifinDepartment of Dermatology, Oregon Health and Science University, Portland, Oregon.
David J MargolisDepartment of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.
Robert A Silvermanprivate practice, Fairfax, Virginia.
Eric L SimpsonDepartment of Dermatology, Oregon Health and Science University, Portland, Oregon.
Hywel C WilliamsCenter of Evidence-based Dermatology, Nottingham University Hospitals National Health Service Trust, Nottingham, United Kingdom.
Craig A ElmetsDepartment of Dermatology, University of Alabama at Birmingham, Birmingham, Alabama.
Julie BlockNational Eczema Association, San Rafael, California.
Christopher G HarrodAmerican Academy of Dermatology, Schaumburg, Illinois.
Wendy Smith BegolkaAmerican Academy of Dermatology, Schaumburg, Illinois. Electronic address: wsmithbegolka@aad.org.
Robert SidburyDepartment of Dermatology, Seattle Children's Hospital, Seattle, Washington.
Oregon Health & Science University · USAmerican Academy of Dermatology · USUniversity of California San Diego · USUniversity of California, San Francisco · USLurie Children's Hospital · USMayo Clinic · USNational Eczema Association · USNational Health Service · GBNew York University · USNorthwestern University · USSeattle Children's Hospital · USUniversity of Alabama at Birmingham · USUniversity of British Columbia · CAUniversity of Pennsylvania · USUniversity of Tennessee Health Science Center · USWake Forest University · USWestern University of Health Sciences · US

Funding

Vitamin D endocrine system and Protection Against Skin TumorlgenesisP30AR039750 · NIAMS · CASE WESTERN RESERVE UNIVERSITY · PI COOPER, KEVIN D · 1988 to 2015
$9.1M
Genetic Influence in Pediatric PsoriasisK23AR060274 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI TOM, WYNNIS L · 2011 to 2015
$663k
NIAMS NIH HHS K23 AR060274NIAMS NIH HHS K23AR060274NIAMS NIH HHS P30 AR039750
6 · The paper itself

Abstract

Atopic dermatitis is a common and chronic, pruritic inflammatory skin condition that can affect all age groups. This evidence-based guideline addresses important clinical questions that arise in its management. In this second of 4 sections, treatment of atopic dermatitis with nonpharmacologic interventions and pharmacologic topical therapies are reviewed. Where possible, suggestions on dosing and monitoring are given based on available evidence.

Indexed as

Calcineurin InhibitorsPractice Guidelines as TopicAdministration, TopicalAdrenal Cortex HormonesChronic DiseaseDermatitis, AtopicEmollientsEvidence-Based MedicineHistamine AntagonistsHumansAdrenal Cortex HormonesCalcineurin InhibitorsEmollientsHistamine Antagonistsantihistaminesantimicrobialsatopic dermatitisbathingcalcineurin inhibitorscorticosteroidsemollientstopicalswet wraps

Identifiers

PMID24813302
PMCPMC4326095
OpenAlexW2142327072

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.