ReviewBioMed research international2014
The evolution of cardiovascular surgery in elderly patient: a review of current options and outcomes.
Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05279898 (Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies - the PATHFINDER II Study), which is not on this map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies - the PATHFINDER II Study
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Modified ultrafiltration reduces postoperative blood loss and transfusions in adult cardiac surgery: a meta-analysis of randomized controlled trials.Interactive cardiovascular and thoracic surgery · 2021Pooled it
- The incremental predictive value of frailty measures in elderly patients undergoing cardiac surgery: A systematic review.Clinical cardiology · 2018Pooled it
- [Cardiac surgery in the elderly].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2017Pooled it
- Ruptured sinus of Valsalva aneurysm with associated ventricular septal defect: a case report.International journal of surgery case reports · 2026Article
- Anatomy-driven strategies and mid-term outcomes of branched endovascular repair of the aortic arch: a single-center cohort study.Journal of cardiothoracic surgery · 2026Article
- Early postoperative 6-minute walk test in cardiac surgery patients: an observational study assessing safety, feasibility, and predictors of completion in India.Acute and critical care · 2025Article
- Article
- Characteristics, outcomes, and complications among nonagenarian and centenarian patients admitted to the intensive care unit: a scoping review.Critical care (London, England) · 2025Article
- Association between serum creatinine-to-albumin ratio and 28-day mortality in intensive care unit patients following cardiac surgery: analysis of mimic-iv data.BMC cardiovascular disorders · 2025Article
- Outcomes and complications among nonagenarians undergoing cardiac surgery: A scoping review.PloS one · 2025Article
- Real-world safety and effectiveness of inhaled nitric oxide therapy for pulmonary hypertension during the perioperative period of cardiac surgery: a post-marketing study of 2817 patients in Japan.General thoracic and cardiovascular surgery · 2024Article
- Review
- Del Nido cardioplegia or potassium induces Nrf2 and protects cardiomyocytes against oxidative stress.American journal of physiology. Cell physiology · 2023Article
- Outcomes and complications of nonagenarians undergoing cardiac surgery: a scoping review protocol.BMJ open · 2023Article
- Effects of Atrial Fibrillation Radiofrequency Ablation in Patients Aged > 75 Years Undergoing Mitral Valve Surgery.Journal of clinical medicine · 2023Article
- Isolated annuloplasty in elderly patients with secondary mitral valve regurgitation: short- and long-term outcomes with a less invasive approach.Frontiers in cardiovascular medicine · 2023Article
- The value of the ACEF II score in Chinese patients with elective and non-elective cardiac surgery.BMC cardiovascular disorders · 2022Article
- A new model to predict acute kidney injury after cardiac surgery in patients with renal insufficiency.Renal failure · 2022Article
- Geographical distribution of authorship for leading cardiothoracic surgery journals.Journal of cardiac surgery · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Due to the increase in average life expectancy and the higher incidence of cardiovascular disease with advancing age, more elderly patients present for cardiac surgery nowadays. Advances in pre- and postoperative care have led to the possibility that an increasing number of elderly patients can be operated on safely and with a satisfactory outcome. Currently, coronary artery bypass surgery, aortic and mitral valve surgery, and major surgery of the aorta are performed in elderly patients. The data available show that most cardiac surgical procedures can be performed in elderly patients with a satisfactory outcome. Nevertheless, the risk for these patients is only acceptable in the absence of comorbidities. In particular, renal dysfunction, cerebrovascular disease, and poor clinical state are associated with a worse outcome in elderly patients. Careful patient selection, flawless surgery, meticulous hemostasis, perfect anesthesia, and adequate myocardial protection are basic requirements for the success of cardiac surgery in elderly patients. The care of elderly cardiac surgical patients can be improved only through the strict collaboration of geriatricians, anesthesiologists, cardiologists, and cardiac surgeons, in order to obtain a tailored treatment for each individual patient.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.