ArticleEvidence-based complementary and alternative medicine : eCAM2014
Effects of acupuncture applied to sanyinjiao with different stimuli on uterine contraction and microcirculation in rats with dysmenorrhea of cold coagulation syndrome.
Article in Evidence-based complementary and alternative medicine : eCAM, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 9 citations in OpenAlex.
- Physiological impact of nanoporous acupuncture needles: Laser Doppler perfusion imaging in healthy volunteers.PloS one · 2019Trial
- Effects of low-frequency and high-frequency electroacupuncture pretreatment on the COX-2/mPGES-1/PGE2 pathway in a rat model of cold-coagulation dysmenorrhea.Frontiers in immunology · 2025Article
- Acupuncture Alleviates Menstrual Pain in Rat Model via Suppressing Eotaxin/CCR3 Axis to Weak EOS-MC Activation.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Regulation of Mild Moxibustion on Uterine Vascular and Prostaglandin Contents in Primary Dysmenorrhea Rat Model.Evidence-based complementary and alternative medicine : eCAM · 2021Article
- Effect of cold stress on ovarian & uterine microcirculation in rats and the role of endothelin system.Reproductive biology and endocrinology : RB&E · 2020Article
- Traditional Acupuncture Meets Modern Nanotechnology: Opportunities and Perspectives.Evidence-based complementary and alternative medicine : eCAM · 2019Review
- Hierarchical Micro/Nano-Porous Acupuncture Needles Offering Enhanced Therapeutic Properties.Scientific reports · 2016Article
- The effect of acupressure on muscle cramps in patients undergoing hemodialysis.Iranian journal of nursing and midwifery researchArticle
Corrections and comments
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Authors and funding
15 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we try to evaluate the effects of acupuncture stimulation with different amounts at Sanyinjiao (SP6) on uterine contraction and uterus microcirculation in rats with dysmenorrhea of cold coagulation syndrome and to explore whether there is direct relativity between "De qi" and needle stimulus intensity. Diestrus female rats were randomly divided into 4 groups, including saline control group, model control group, "A" stimulus group (with strong stimulus), and "B" stimulus group (with weak stimulus). We found that dysmenorrhea rats of the cold coagulation syndrome present a high intensity in uterine tension and high contraction of microvascular diameter. Acupuncture applied with two different stimuli could relieve the symptoms, but, compared with "B" stimulus, "A" stimulus leads to better outcomes on reducing uterine contraction and increasing diameter of uterine microvascular; moreover, hand manipulation during needling mediates the curative effect on the microvascular diameter. Our finding indicates that using thick needles and deep insertion with hand manipulation are more effective and achieve desired level of "De qi" in dysmenorrhea rats.
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Registered trials
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