Evidence map›Paper›PMID 24812065›Full record

SynthesisTransactions of the Royal Society of Tropical Medicine and Hygiene2014

Human diarrhea infections associated with domestic animal husbandry: a systematic review and meta-analysis.

Laura D Zambrano, Karen Levy, Neia P Menezes, Matthew C Freeman

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Transactions of the Royal Society of Tropical Medicine and Hygiene, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 6 pooled it
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 6 syntheses or guidelines pooled it, 207 citations in OpenAlex.

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  4. Measurement in the study of human exposure to animal feces: A systematic review and audit.International journal of hygiene and environmental health · 2023
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71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laura D ZambranoDepartment of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd NE, CNR 2027, Atlanta, GA 30322, USA.
Karen LevyDepartment of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd NE, CNR 2027, Atlanta, GA 30322, USA.
Neia P MenezesDepartment of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd NE, CNR 2027, Atlanta, GA 30322, USA.
Matthew C FreemanDepartment of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Rd NE, CNR 2027, Atlanta, GA 30322, USA mcfreem@emory.edu.
Emory University · US

Funding

Impacts of Human Movement on Regional Strain Distribution of Diarrheagenic E.coliK01AI103544 · NIAID · EMORY UNIVERSITY · PI LEVY, KAREN · 2013 to 2017
$655k
NIAID NIH HHS K01 AI103544NIAID NIH HHS K01AI103544
6 · The paper itself

Abstract

Domestic animal husbandry, a common practice globally, can lead to zoonotic transmission of enteric pathogens. However, this risk has received little attention to date. This systematic review and meta-analysis examines the evidence for an association between domestic exposure to food-producing animals and cases of human diarrhea and specific enteric infections. We performed a systematic review of available literature to examine domestic livestock and poultry as risk factors for diarrhea and applied pre-determined quality criteria. Where possible, we carried out meta-analysis of specific animal-pathogen pairs. We found consistent evidence of a positive association between exposure to domestic food-producing animals and diarrheal illness across a range of animal exposures and enteric pathogens. Out of 29 studies included in the review, 20 (69.0%) reported a positive association between domestic animal exposure and diarrhea. Domestic exposure to poultry revealed a substantial association with human campylobacteriosis (OR 2.73, 95% CI 1.90-3.93). Our results suggest that domestic poultry and livestock exposures are associated with diarrheal illness in humans. Failure to ascertain the microbial cause of disease may mask this effect. Exposure to domestic animals should be considered a risk factor for human diarrheal illness and additional studies may identify potential mitigation strategies to address this risk.

Indexed as

Animal HusbandryAnimalsAnimals, DomesticCampylobacter InfectionsDiarrheaFecesHumansPoultryPoultry DiseasesQualitative ResearchRisk FactorsZoonosesAnimal husbandryDiarrheaDomestic animalsHygieneSystematic review

Identifiers

PMID24812065
PMCPMC4023907
OpenAlexW2118240814

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.