ArticleInternational journal of clinical oncology2015
Administration of chemotherapy via the median cubital vein without implantable central venous access ports: port-free chemotherapy for metastatic colorectal cancer patients.
Article in International journal of clinical oncology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Phase 2 study of perioperative chemotherapy with SOX and surgery for stage III colorectal cancer (SOS3 study).Scientific reports · 2019Trial
- A single-arm Phase II validation study of preventing oxaliplatin-induced hypersensitivity reactions by dexamethasone: the AVOID trial.Drug design, development and therapy · 2015Trial
- Use of Peripheral Intravenous Access in Patients Undergoing Chemotherapy for Testicular Cancer.JCO oncology practice · 2024Article
- Article
- Retrospective outcome analysis of rates and types of complications after 8654 minimally invasive radiological port implantations via the subclavian vein without ultrasound guidance.La Radiologia medica · 2019Article
- The effect of nigella sativa oil on the prevention of phlebitis induced by chemotherapy: a clinical trial.BioMedicine · 2019Article
- Thromboprophylaxis and the route of administration of chemotherapy in testicular cancer patients in German-speaking countries.World journal of urology · 2018Article
- Preventive effect of pre-warming, hot compress, and pH adjustment in oxaliplatin-induced venous pain.International journal of clinical pharmacy · 2017Observational
- Phase II study on early start of chemotherapy after excising primary colorectal cancer with distant metastases (Pearl Star 02).Annals of gastroenterological surgery · 2017Article
- (18)F-Fluorodeoxyglucose positron emission tomography ((18)F-FDG PET) for the early detection of response to neoadjuvant chemotherapy for locally advanced rectal cancer.Surgery today · 2016Article
- Objective evaluation of oxaliplatin-induced vascular pain secondary to peripheral vein administration.SpringerPlus · 2016Article
- Can grade 2 neutropenia predict the risk of grade 3 neutropenia in metastatic colorectal cancer patients treated with chemotherapy?Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015Article
- Subjective and objective assessment of oxaliplatin-induced peripheral neuropathy.SpringerPlus · 2015Article
- Difference in Neutropenia due to Administration Schedule of TAS-102.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRepeated venous punctures are usually required during chemotherapy administration for cancer patients. Central venous catheters and implantable port systems have substantially facilitated vascular access, and safe, easy-to-handle port systems have become an integral part of daily clinical routines in oncology. However, several serious complications are associated with central venous ports (CV-ports), and recent developments of combined oral capecitabine and oxaliplatin (XELOX) therapies allow CV-port-free administration. In this study, the safety and efficacy of CV-port-free chemotherapy administration via the median cubital vein was assessed in metastatic colorectal cancer patients.
methodsThis study included 144 patients who received XELOX + bevacizumab (BV) or XELOX therapy for metastatic colorectal cancer without CV-port implantation.
resultsEighty-five patients experienced transient vascular pain. The drip infusion route was switched to the opposite side following vascular pain in only 1 patient. No patients required CV-port implantation or delayed treatment due to adverse events associated with drug administration via the peripheral vein. Grade 3 or higher hemotoxicity and grade 3 or higher non-hematological toxicity was noted in 12.5 and 17.4 % of patients, respectively.
conclusionsPort-free-chemotherapy administration via the median cubital vein is appropriate for patients with colorectal cancer, thereby avoiding complications associated with CV-ports.
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