ArticleJournal of perinatology : official journal of the California Perinatal Association2014
Maternal obesity and increased risk for autism and developmental delay among very preterm infants.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 6 syntheses or guidelines pooled it, 109 citations in OpenAlex.
- Identifying the risk factors of autism spectrum disorders in infants born preterm: a systematic review and meta-analysis.European child & adolescent psychiatry · 2026Pooled it
- Mapping evidence on maternal metabolic conditions and child neurodevelopment in the Caribbean: a scoping review.Frontiers in nutrition · 2026Pooled it
- Association between parental body mass index and autism spectrum disorder: a systematic review and meta-analysis.European child & adolescent psychiatry · 2019Pooled it
- Maternal pre-pregnancy obesity and child neurodevelopmental outcomes: a meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2018Pooled it
- Maternal pre-pregnancy obesity and childhood physical and cognitive development of children: a systematic review.International journal of obesity (2005) · 2016Pooled it
- Association Between Maternal Obesity and Autism Spectrum Disorder in Offspring: A Meta-analysis.Journal of autism and developmental disorders · 2016Pooled it
- Maternal metformin treatment in obese pregnant dams normalizes neonatal sensory-motor reflexes.Molecular and cellular pediatrics · 2026Article
- Effects of Maternal Obesity on Fetal Cerebral Glucose Transporter Expression.bioRxiv : the preprint server for biology · 2026Article
- A Review of the Effects of Maternal and Paternal Obesity on Neurodevelopmental Disorders and Related Neurobiology in Rodent and Human Offspring.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Impact of high maternal body mass index on fetal cerebral cortical and cerebellar volumes.Journal of perinatal medicine · 2025Article
- Maternal Obesity and Neurodevelopment of the Offspring.Nutrients · 2025Review
- Maternal Prepregnancy Obesity and Offspring Intelligence Quotient at 5 Years: A Multicohort Analysis.Paediatric and perinatal epidemiology · 2025Article
- The role of nutrition and gut microbiome in childhood brain development and behavior.Frontiers in nutrition · 2025Review
- Reliability of a short diet and vitamin supplement questionnaire for retrospective collection of maternal nutrient intake.Global epidemiology · 2024Article
- Possible relationship between pre-pregnancy maternal body mass index and offspring hippocampus: An experimental study in albino Wistar rat.Open veterinary journal · 2024Article
- Maternal Eating Disorders, Body Mass Index, and Offspring Psychiatric Diagnoses.JAMA network open · 2024Article
- Prenatal Diabetes and Obesity: Implications for Autism Spectrum Disorders in Offspring - A Comprehensive Review.Medical science monitor : international medical journal of experimental and clinical research · 2024Review
- Associations between maternal metabolic conditions and neurodevelopmental conditions in offspring: the mediating effects of obstetric and neonatal complications.BMC medicine · 2023Article
- The association of maternal overweight on long-term neurodevelopmental outcomes in premature infants (< 29 weeks) at 18-24 months corrected age.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Severe obesity and global developmental delay in preschool children: Findings from a Canadian Paediatric Surveillance Program study.Paediatrics & child health · 2023Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThirty-five percent of women of child-bearing age are obese, and there is evidence that maternal obesity may increase the risk for adverse neurodevelopmental outcome. However, research regarding obesity and neurodevelopment among children born preterm is limited. This study aimed to determine associations between maternal obesity and neurodevelopment in very preterm children at age 2 years. STUDY
designMaternal/infant dyads (n=62) born ⩽30 weeks gestation were enrolled in a prospective cohort study at a level-III neonatal intensive care unit. Mothers were classified as obese or non-obese based on pre-pregnancy body mass index. Infants underwent magnetic resonance imaging at term equivalent and developmental testing at age 2. Maternal obesity was investigated for associations with neurodevelopment.
resultMaternal obesity was associated with positive screen for autism (odds ratio=9.88, P=0.002) and lower composite language scores (β=-9.36, (confidence interval=-15.11, -3.61), P=0.002).
conclusionMaternal obesity was associated with adverse neurodevelopmental outcome at age 2 in this cohort of very preterm children. This study requires replication, but may support targeted surveillance of infants born to women with maternal obesity.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.