Evidence map›Paper›PMID 24810245›Full record

ArticleCancer investigation2014

Tumor acquisition for biomarker research in lung cancer.

Marvaretta Stevenson, Jared Christensen, Debra Shoemaker, Traci Foster, William T Barry, Betty C Tong, Momen Wahidi, Scott Shofer, Michael Datto, Geoffrey Ginsburg and 3 more

Abstract read
In one paragraph

Article in Cancer investigation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Marvaretta Stevenson1Duke Cancer Institute, Durham, North Carolina, USA;
Jared Christensen
Debra Shoemaker
Traci Foster
William T Barry
Betty C Tong
Momen Wahidi
Scott Shofer
Michael Datto
Geoffrey Ginsburg
Jeffrey Crawford
Thomas D'Amico
Neal Ready

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI DONNA NIEDZWIECKI · 1985 to 2026
$174.8M
Core Clinical Centers for the CTSNUM1HL088953 · NHLBI · DUKE UNIVERSITY · PI SMITH, PETER K · 2013 to 2017
$2.5M
NCI NIH HHS P30 CA014236NHLBI NIH HHS UM1 HL088953
6 · The paper itself

Abstract

The biopsy collection data from two lung cancer trials that required fresh tumor samples be obtained for microarray analysis were reviewed. In the trial for advanced disease, microarray data were obtained on 50 patient samples, giving an overall success rate of 60.2%. The majority of the specimens were obtained through CT-guided lung biopsies (N = 30). In the trial for early-stage patients, 28 tissue specimens were collected from excess tumor after surgical resection with a success rate of 85.7%. This tissue procurement program documents the feasibility in obtaining fresh tumor specimens prospectively that could be used for molecular testing.

Indexed as

Biomarkers, TumorBiopsyCarcinoma, Non-Small-Cell LungClinical Trials as TopicFemaleGene Expression Regulation, NeoplasticHumansLung NeoplasmsMaleMutationNeoplasm StagingOligonucleotide Array Sequence AnalysisRNABiomarkers, TumorRNABioinformaticsGene profilingLung cancer

Identifiers

PMID24810245
PMCPMC4336177

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.