Combined administration of oxycodone/naloxone in chronic osteo-articular diseases pain therapy.

Palomba Rosa, Miralto Federica, Vinciguerra Annamaria, Salvato Fabiana, Vaccarella Anna

Open access · greenAbstract readReview

In one paragraph

Review in Translational medicine @ UniSa, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

0.6field-weighted citation impact, top 27% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Palomba RosaDepartment of Anesthesia, Rianimation, Intensive Therapy and Pain Therapy University "Federico II" Naples , Italy.

Miralto FedericaDepartment of Anesthesia, Rianimation, Intensive Therapy and Pain Therapy University "Federico II" Naples , Italy.

Vinciguerra AnnamariaDepartment of Anesthesia, Rianimation, Intensive Therapy and Pain Therapy University "Federico II" Naples , Italy.

Salvato FabianaDepartment of Anesthesia, Rianimation, Intensive Therapy and Pain Therapy University "Federico II" Naples , Italy.

Vaccarella AnnaDepartment of Anesthesia, Rianimation, Intensive Therapy and Pain Therapy University "Federico II" Naples , Italy.

Federico II University Hospital · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is the analysis of the beneficial impact of using opioid receptor antagonist associated to opioid analgesic on the quality of life in patients suffering from chronic non-cancer pain. We recruited 60 patients suffering from osteo-articular diseases who were randomized into two groups of treatment. The group A was treated with the association of opioid receptor antagonist and opioid agonist, represented by Oxycodone. The group B was treated with the opioid analgesics Oxycodone, transdermal Fentanil, and Hidromorphone, without the opioid antagonist. The end-points assessed were the duration of titration, the average reached dosage, the duration of the stability of dosage and the opioid-induced constipation (OIC) using the BFI.

Indexed as

chronic osteo-articular diseaseschronic painoxycodone/naloxone

Identifiers

PMID24809034

PMCPMC4012374

OpenAlexW2142252889

What OpenQuestion holds

Textmetadata

LicenceCC BY-NC

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.