Evidence map›Paper›PMID 24808851›Full record

ReviewFrontiers in human neuroscience2014

The co-occurrence of autism and attention deficit hyperactivity disorder in children - what do we know?

Yael Leitner

Registry-linked trialAbstract readReview
In one paragraph

Review in Frontiers in human neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03337646 (A Multi-Center, Open Label, Evaluation of the Effect and Safety of Lisdexamfetamine in Children Aged 6-12 With Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder), which is not on this map. Cited by 199 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
199citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03337646 phase4completednot on this mapstarted 2018, after this paper: background citation

A Multi-Center, Open Label, Evaluation of the Effect and Safety of Lisdexamfetamine in Children Aged 6-12 With Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder

TypeinterventionalSponsorJPM van Stralen Medicine ProfessionalRan2018 to 2023Enrolled48ConditionsAttention Deficit Hyperactivity Disorder, Autism Spectrum DisorderArmsLisdexamfetamine Dimesylate
3 · Its place in the literature

Who cites it

199 citing papers in PubMed, 6 syntheses or guidelines pooled it.

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139 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Yael LeitnerChild Development Center, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center , Tel Aviv , Israel ; Sackler School of Medicine, Tel Aviv University , Tel Aviv , Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Symptoms of attention deficit hyperactivity disorder (ADHD) and autistic spectrum disorder (ASD) often co-occur. The DSM-IV had specified that an ASD diagnosis is an exclusion criterion for ADHD, thereby limiting research of this common clinical co-occurrence. As neurodevelopmental disorders, both ASD and ADHD share some phenotypic similarities, but are characterized by distinct diagnostic criteria. The present review will examine the frequency and implications of this clinical co-occurrence in children, with an emphasis on the available data regarding pre-school age. The review will highlight possible etiologies explaining it, and suggest future research directions necessary to enhance our understanding of both etiology and therapeutic interventions, in light of the new DSM-V criteria, allowing for a dual diagnosis.

Indexed as

attention deficit hyperactivity disorderautistic spectrum disordersco-morbidityco-occurrencediagnostic and statistical manual

Identifiers

PMID24808851
PMCPMC4010758

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.