ArticleMycobiology2014
Molecular Epidemiology of Clinical Cryptococcus neoformans Isolates in Seoul, Korea.
Article in Mycobiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Analysis of fungal diversity in the feces ofFrontiers in veterinary science · 2024Article
- Article
- Article
- The Predominance of a Specific Genotype ofComputational and mathematical methods in medicine · 2022Article
- Multilocus Sequence Typing of Clinical Isolates of Cryptococcus from India.Mycopathologia · 2021Article
- Associations betweenJournal of fungi (Basel, Switzerland) · 2021Review
- Molecular Epidemiology Reveals Low Genetic Diversity amongPathogens (Basel, Switzerland) · 2020Article
- Multi-locus Sequence Typing and Whole Genome Sequence Analysis of Cryptococcus neoformans Isolated from Clinical Specimens in Vajira Hospital, Bangkok, Thailand.Mycopathologia · 2020Article
- Epidemiology of fungal infections in China.Frontiers of medicine · 2018Review
- Genotypes of Clinical and Environmental Isolates of Cryptococcus neoformans and Cryptococcus gattii in Korea.Mycobiology · 2015Article
Corrections and comments
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Authors and funding
4 authors.
Funding
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Abstract
Cryptococcal infection is primarily caused by two species, Cryptococcus neoformans and C. gattii. Between the two species, C. neoformans var. grubii is the major causative agent of cryptococcosis in Asia. We investigated the molecular characteristics of 46 isolates of C. neoformans from patients with cryptococcosis between 2008 and 2012 in Seoul, Korea. All the isolates were determined to be C. neoformans var. grubii (serotype A), mating type MATα, and molecular type VNI by PCR-restriction fragment length polymorphism of the URA5 gene. Multilocus sequencing type (MLST) analysis using the International Society of Human and Animal Mycoses (ISHAM) consensus MLST scheme identified two sequence types (ST). Out of the 46 strains, 44 (95.7%) were identified as ST5, and remaining 2 were identified as ST31. Our study revealed that the clinical strains of C. neoformans in Korea are genetically homogeneous with the VNI/ST5 genotypes, and new appearance of VNI/ST31 genotype may serve as an important indicator of global genetic analysis.
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