Evidence map›Paper›PMID 24808630›Full record

ArticleResearch Evaluation2013

Modeling the dissemination and uptake of clinical trials results.

Scott R Rosas, Jeffrey T Schouten, Marie T Cope, Jonathan M Kagan

Abstract read
In one paragraph

Article in Research Evaluation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
10.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. A bibliometric perspective to the most cited diabetes articles.Journal of diabetes and metabolic disorders · 2023
    Article
  3. Methods for identifying biomedical translation: a systematic review.American journal of translational research · 2022
    Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Anatomy of success: 100 most cited articles in diabetes research.Therapeutic advances in endocrinology and metabolism · 2015
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Scott R RosasConcept Systems, Inc., 136 East State Street, Ithaca, NY 14850-5546, Office of HIV/AIDS Network Coordination, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, E2-112, Seattle, WA 98109-1024 and Division of Clinical Research, NIAID, NIH, 6700B Rockledge Drive, Room 1102, Bethesda, MD 20892-7609.
Jeffrey T SchoutenConcept Systems, Inc., 136 East State Street, Ithaca, NY 14850-5546, Office of HIV/AIDS Network Coordination, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, E2-112, Seattle, WA 98109-1024 and Division of Clinical Research, NIAID, NIH, 6700B Rockledge Drive, Room 1102, Bethesda, MD 20892-7609.
Marie T CopeConcept Systems, Inc., 136 East State Street, Ithaca, NY 14850-5546, Office of HIV/AIDS Network Coordination, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, E2-112, Seattle, WA 98109-1024 and Division of Clinical Research, NIAID, NIH, 6700B Rockledge Drive, Room 1102, Bethesda, MD 20892-7609.
Jonathan M KaganConcept Systems, Inc., 136 East State Street, Ithaca, NY 14850-5546, Office of HIV/AIDS Network Coordination, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, E2-112, Seattle, WA 98109-1024 and Division of Clinical Research, NIAID, NIH, 6700B Rockledge Drive, Room 1102, Bethesda, MD 20892-7609.
Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South Africa · ZA

Funding

Leadership Group for a Global HIV Vaccine Clinical Trials NetworkU01AI068614 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI COREY, LAWRENCE · 2006 to 2010
$181.5M
Intramural NIH HHS Z99 AI999999NIAID NIH HHS N01 AI050022NIAID NIH HHS U01 AI068614
6 · The paper itself

Abstract

A select set of highly cited publications from the National Institutes of Health (NIH) HIV/AIDS Clinical Trials Networks was used to illustrate the integration of time interval and citation data, modeling the progression, dissemination, and uptake of primary research findings. Following a process marker approach, the pace of initial utilization of this research was measured as the time from trial conceptualization, development and implementation, through results dissemination and uptake. Compared to earlier studies of clinical research, findings suggest that select HIV/AIDS trial results are disseminated and utilized relatively rapidly. Time-based modeling of publication results as they meet specific citation milestones enabled the observation of points at which study results were present in the literature summarizing the evidence in the field. Evaluating the pace of clinical research, results dissemination, and knowledge uptake in synthesized literature can help establish realistic expectations for the time course of clinical trials research and their relative impact toward influencing clinical practice.

Indexed as

citation milestonesdisseminationscientific outputuptake

Identifiers

PMID24808630
PMCPMC3745267
OpenAlexW2082964577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.