ArticleThe Plant cell2014
Tools and Strategies to Match Peptide-Ligand Receptor Pairs.
Article in The Plant cell, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
55 citing papers in PubMed, 121 citations in OpenAlex.
- Plant peptide hormones: three decades of discovery and emerging paradigms.Plant physiology · 2026Review
- A tomato MIK2-clade receptor is involved in the perception of a Fusarium-derived elicitor.The New phytologist · 2026Article
- An IDA peptide from Boea hygrometrica enhances desiccation tolerance but lacks activity in Arabidopsis.Planta · 2026Article
- Genetic Diversity, Predictive Protein Structures, and Interaction Networks of Cysteine-Rich Receptor-Like Kinases inComputational and structural biotechnology journal · 2026Article
- Abscission zones: cellular interfaces for the programmed separation of organs.Annals of botany · 2025Review
- Large-scale pairing identifies a soybean phytocytokine-receptor module conferring disease resistance.Nature plants · 2025Article
- MhIDA small peptides modulate the growth and development of roots in Malus hupehensis.Plant cell reports · 2025Article
- Peptide hormones in plants.Molecular horticulture · 2025Review
- Article
- Rapid Identification of Peptide-Receptor-Coreceptor Complexes in Protoplasts.Methods in molecular biology (Clifton, N.J.) · 2024Article
- LuBiA (Luciferase-Based Binding Assay): Glowing Peptides as Sensitive Probes to Study Ligand-Receptor Interactions.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Isothermal Titration Calorimetry to Study Plant Peptide Ligand-Receptor Interactions.Methods in molecular biology (Clifton, N.J.) · 2024Article
- The rose INFLORESCENCE DEFICIENT IN ABSCISSION-LIKE genes, RbIDL1 and RbIDL4, regulate abscission in an ethylene-responsive manner.Plant cell reports · 2023Article
- Adaptive protein evolution through length variation of short tandem repeats inScience advances · 2023Article
- HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides.Nature communications · 2022Article
- Characterization of Two Ethephon-InducedGenes · 2021Article
- EPIP-Evoked Modifications of Redox, Lipid, and Pectin Homeostasis in the Abscission Zone of Lupine Flowers.International journal of molecular sciences · 2021Article
- Signaling Peptides Regulating Abiotic Stress Responses in Plants.Frontiers in plant science · 2021Review
- A receptor-like protein mediates plant immune responses to herbivore-associated molecular patterns.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Processing and Formation of Bioactive CLE40 Peptide Are Controlled by Posttranslational Proline Hydroxylation.Plant physiology · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Peptide signals have emerged as an important class of regulators in cell-to-cell communication in plants. Several families of small, secreted proteins with a conserved C-terminal Pro-rich motif have been identified as functional peptide signals in Arabidopsis thaliana. These proteins are presumed to be trimmed proteolytically and undergo posttranslational modifications, such as hydroxylation of Pro residues and glycosylation, to form mature, bioactive signals. Identification and matching of such ligands with their respective receptors remains a major challenge since the genes encoding them often show redundancy and low expression restricted to a few cells or particular developmental stages. To overcome these difficulties, we propose the use of ectopic expression of receptor genes in suitable plant cells like Nicotiana benthamiana for testing ligand candidates in receptor output assays and in binding studies. As an example, we used the IDA peptide HAE/HSL2 receptor signaling system known to regulate floral organ abscission. We demonstrate that the oxidative burst response can be employed as readout for receptor activation by synthetic peptides and that a new, highly sensitive, nonradioactive labeling approach can be used to reveal a direct correlation between peptide activity and receptor affinity. We suggest that these approaches will be of broad value for the field of ligand-receptor studies in plants.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.