ArticleBipolar disorders2014
The Bipolar Prodrome Symptom Interview and Scale-Prospective (BPSS-P): description and validation in a psychiatric sample and healthy controls.
Article in Bipolar disorders, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02456545 (Improving Early Recognition and Intervention in At-risk Stages of Bipolar Disorders), which is not on this map. Cited by 39 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Improving Early Recognition and Intervention in At-risk Stages of Bipolar Disorders
Who cites it
39 citing papers in PubMed, 2 syntheses or guidelines pooled it, 100 citations in OpenAlex.
- Meta-analytic prevalence of comorbid mental disorders in individuals at clinical high risk of psychosis: the case for transdiagnostic assessment.Molecular psychiatry · 2023Pooled it
- Can We Predict Psychosis Outside the Clinical High-Risk State? A Systematic Review of Non-Psychotic Risk Syndromes for Mental Disorders.Schizophrenia bulletin · 2018Pooled it
- Trial
- Jumping to Conclusions in First-Episode Psychosis and Bipolar Disorder.Early intervention in psychiatry · 2026Article
- Functional Outcome Prediction in Young Adults With Mental Health Symptoms Using Machine Learning and Large Language Models: Longitudinal Observational Study.JMIR mental health · 2026Observational
- Co-existence of clinical high-risk for psychosis and bipolar disorder: a multi-dimensional psychopathological analysis.BMC psychiatry · 2026Article
- Development and validation of a prognostic model and risk calculator for the estimation of bipolar-spectrum disorder risk in hospitalised adolescents with non-psychotic/non-bipolar mental disorders.Molecular psychiatry · 2026Article
- Creativity and transition to bipolar disorder: a prospective analysis from the early-bipolife study.International journal of bipolar disorders · 2025Article
- Catching the Storm Before It Breaks: Advancing Early Diagnosis and Intervention in Bipolar Disorder.Life (Basel, Switzerland) · 2025Review
- My risk perception; perspectives from youth at familial risk for bipolar disorder: a qualitative study.BMC psychiatry · 2025Article
- Advancing the prediction of factors associated with bipolar disorder risk: utilizing early recognition tools and polygenic risk scores.International journal of bipolar disorders · 2025Article
- Longitudinal evolution of the transdiagnostic prodrome to severe mental disorders: a dynamic temporal network analysis informed by natural language processing and electronic health records.Molecular psychiatry · 2025Article
- Transdiagnostic Clinical Staging in Youth Mental Health: A primer for clinical practice.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Review
- Towards a youth mental health paradigm: a perspective and roadmap.Molecular psychiatry · 2023Review
- Machine Learning Prediction of Estimated Risk for Bipolar Disorders Using Hippocampal Subfield and Amygdala Nuclei Volumes.Brain sciences · 2023Article
- The clinical characterization of the adult patient with bipolar disorder aimed at personalization of management.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2022Article
- A cohort study of adolescents with depression in China: tracking multidimensional outcomes and early biomarkers for intervention.General psychiatry · 2022Article
- Affective lability as a prospective predictor of subsequent bipolar disorder diagnosis: a systematic review.International journal of bipolar disorders · 2021Review
- Individuals at increased risk for development of bipolar disorder display structural alterations similar to people with manifest disease.Translational psychiatry · 2021Article
- Clinical Risk Constellations for the Development of Bipolar Disorders.Medicina (Kaunas, Lithuania) · 2021Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
objectiveThe aim of the present study was to investigate the psychometric properties of the Bipolar Prodrome Symptom Interview and Scale-Prospective (BPSS-P), the first specific interview for emerging bipolar disorder (BD) symptoms.
methodsA total of 205 youth aged 12-23 years and/or their caregivers underwent BPSS-P interviews: 129 patients with mood spectrum disorders [depression spectrum disorder (n = 77), mood disorder not otherwise specified (NOS) (n = 27), BD-NOS (n = 14), bipolar I disorder (BD-I)/bipolar II disorder (BD-II)/cyclothymia (n = 11), 34 with non-mood spectrum disorders, and 42 healthy controls (HCs)]. We used Cronbach's α to assess internal consistency; intra-class correlation (ICC) for inter-rater reliability; Spearman's rho for convergent validity with the Young Mania Rating Scale (YMRS), General Behavior Inventory-10-item Mania Form (GBI-M-10), and Cyclothymic-Hypersensitive Temperament (CHT) scale; and analysis of variance for discriminatory power between diagnostic groups.
resultsInternal consistency was good to very good for the BPSS-P Mania (Cronbach's α = 0.87), Depression (Cronbach's α = 0.89), and General Symptom indices (Cronbach's α = 0.74). Inter-rater reliability was high for the BPSS-P Total score (ICC = 0.939), and BPSS-P Mania (ICC = 0.934), Depression (ICC = 0.985), and General (ICC = 0.981) indices. Convergent validity was large (ρ ≥ 0.50) between the BPSS-P Mania Index and YMRS, GBI-M-10, and CHT; BPSS-P Depression Index and Montgomery-Åsberg Depression Rating Scale (MADRS) and CHT; and BPSS-P General Index and GBI-M-10 and CHT. Expectedly, convergent validity was small (ρ = 0.10 to < 0.30) between the BPSS-P Mania Index and MADRS, and BPSS-P Depression Index and YMRS. Furthermore, the BPSS-P and its subscales discriminated each patient group from HCs and from non-mood spectrum patients (except for the BPSS-P General Index). Moreover, the BPSS-P Total score discriminated BD-I/BD-II/cyclothymia from depression spectrum patients, and the BPSS-Mania Index differentiated all three bipolar spectrum groups from depression spectrum patients.
conclusionsThe BPSS-P has good to excellent psychometric properties. Its use across multiple settings and predictive validity requires further investigation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.