Evidence map›Paper›PMID 24807341›Full record

ArticleObstetrics and gynecology2014

Lifetime risk of stress urinary incontinence or pelvic organ prolapse surgery.

Jennifer M Wu, Catherine A Matthews, Mitchell M Conover, Virginia Pate, Michele Jonsson Funk

8 registry-linked trialsAbstract read
In one paragraph

Article in Obstetrics and gynecology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 442 papers, 14 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
442citing papers in PubMed, 14 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02605135 completednot on this mapstarted 2016, after this paper: background citation

Host Response to Pessaries in Microbial Communities of the Postmenopausal

TypeobservationalSponsorLoyola UniversityRan2016 to 2018Enrolled84ConditionsStress Urinary Incontinence, ProlapseArmsContinued Pessary Use
NCT03516292 unknown statusnot on this mapstarted 2018, after this paper: background citation

Potential Biomarkers in the Study of Overactive Bladder in Women

TypeobservationalSponsorAristotle University Of ThessalonikiRan2018 to 2022Enrolled108ConditionsOveractive BladderArmsUrinary Nerve Growth Factor
NCT03821142 naactive not recruitingnot on this mapstarted 2021, after this paper: background citation

Prospective, Multicenter, 60 Months, Single Arm Cohort Study to Evaluate the Efficacy and Safety of the Ultra-Light-Weight Mesh CAlistar S in Transvaginal Pelvic Organ Prolapse Repair

TypeinterventionalSponsorPromedonRan2021 to 2029Enrolled180ConditionsPelvic Organ ProlapseArmsTransvaginal mesh for anterior pelvic organ prolapse repair
NCT03841513 nacompletednot on this mapstarted 2019, after this paper: background citation

Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence

TypeinterventionalSponsorNorthwestern UniversityRan2019 to 2022Enrolled50ConditionsPelvic Organ Prolapse, Urinary Incontinence,Stress, Urinary Incontinence, Urge, Bowel DysfunctionArmsLaparoscopic Burch Colposuspension
NCT05127512 nacompletednot on this mapstarted 2021, after this paper: background citation

Pelvic Floor Disorder Education in the Prenatal Period, a Randomized Controlled Trial

TypeinterventionalSponsorIcahn School of Medicine at Mount SinaiRan2021 to 2022Enrolled94ConditionsPelvic Floor DisordersArmsEducation Video
NCT05688059 nacompletednot on this mapstarted 2023, after this paper: background citation

Is Absorbable Suture Non-Inferior to Permanent Suture in Sacrospinous Ligament Suspension? A Randomized Controlled Trial

TypeinterventionalSponsorAtlantic Health SystemRan2023 to 2025Enrolled49ConditionsPelvic Organ Prolapse, Uterovaginal Prolapse, Vaginal Vault Prolapse, CystoceleArmsAbsorbable Suture and Permanent Suture
NCT05969067 nacompletednot on this mapstarted 2023, after this paper: background citation

Comparing Retroperitoneal Tunneling Versus Dissection Technique During Robotic Assisted Sacrocolpopexy for Pelvic Organ Prolapse

TypeinterventionalSponsorThe University of Texas Medical Branch, GalvestonRan2023 to 2024Enrolled40ConditionsPelvic Organ ProlapseArmsTunneling Technique during RA SCP, Dissection Technique during RA SCP
NCT06391372 phase3active not recruitingnot on this mapstarted 2024, after this paper: background citation

Effect of Local Estriol Treatment Before Vaginal Repair Surgery on Vaginal Tissues and Early Postoperative Pelvic Floor Functions

TypeinterventionalSponsorHatice Tukenmez KurnazRan2024 to 2025Enrolled36ConditionsPelvic Organ Prolapse, Pelvic Floor Disorders, Menopause, Vaginal AtrophyArmsestriol cream
3 · Its place in the literature

Who cites it

442 citing papers in PubMed, 14 syntheses or guidelines pooled it.

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  4. Perioperative interventions in pelvic organ prolapse surgery.The Cochrane database of systematic reviews · 2025
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382 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Jennifer M WuDepartment of Obstetrics and Gynecology, the Center for Women's Health Research, and the Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Catherine A Matthews
Mitchell M Conover
Virginia Pate
Michele Jonsson Funk

Funding

Doubly robust elimination: best practices for comparative effectiveness researchK02HS017950 · AHRQ · UNIV OF NORTH CAROLINA CHAPEL HILL · PI JONSSON FUNK, MICHELE LAURA · 2009 to 2013
$653k
Translational Research in Pelvic Floor DisordersK23HD068404 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, JENNIFER M. · 2011 to 2014
$509k
AHRQ HHS K02 HS017950AHRQ HHS K02HS017950NICHD NIH HHS K23 HD068404NICHD NIH HHS K23HD068404
6 · The paper itself

Abstract

objectiveTo estimate the lifetime risk of stress urinary incontinence (SUI) surgery, pelvic organ prolapse (POP) surgery, or both using current, population-based surgical rates from 2007 to 2011.

methodsWe used a 2007-2011 U.S. claims and encounters database. We included women aged 18-89 years and estimated age-specific incidence rates and cumulative incidence (lifetime risk) of SUI surgery, POP surgery, and either incontinence or prolapse surgery with 95% confidence intervals (CIs). We estimated lifetime risk until the age of 80 years to be consistent with prior studies.

resultsFrom 2007 to 2011, we evaluated 10,177,480 adult women who were followed for 24,979,447 person-years. Among these women, we identified 65,397 incident, or first, SUI and 57,755 incident prolapse surgeries. Overall, we found that the lifetime risk of any primary surgery for SUI or POP was 20.0% (95% CI 19.9-20.2) by the age of 80 years. Separately, the cumulative risk for SUI surgery was 13.6% (95% CI 13.5-13.7) and that for POP surgery was 12.6% (95% CI 12.4-2.7). For age-specific annual risk, SUI demonstrated a bimodal peak at age 46 years and then again at age 70-71 years with annual risks of 3.8 and 3.9 per 1,000 women, respectively. For POP, the risk increased progressively until ages 71 and 73 years when the annual risk was 4.3 per 1,000 women.

conclusionBased on a U.S. claims and encounters database, the estimated lifetime risk of surgery for either SUI or POP in women is 20.0% by the age of 80 years. LEVEL OF EVIDENCE: III.

Indexed as

AdolescentAdultAgedAged, 80 and overFemaleGynecologic Surgical ProceduresHumansIncidenceMiddle AgedPelvic Organ ProlapseUrinary Incontinence, StressUrologic Surgical Procedures

Identifiers

PMID24807341
PMCPMC4174312

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.