Evidence map›Paper›PMID 24806930›Full record

ArticleBiophysical journal2014

Macroscopic phase separation, modulated phases, and microemulsions: a unified picture of rafts.

Roie Shlomovitz, Lutz Maibaum, M Schick

Abstract read
In one paragraph

Article in Biophysical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. A Theoretical Basis for Nanodomains.The Journal of membrane biology · 2022
    Review
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  15. Eliminating the roughness in cholesterol's β-face: does it matter?Langmuir : the ACS journal of surfaces and colloids · 2014
    Article
  16. Article
  17. The many faces of lipid rafts.Biophysical journal · 2014
    Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Roie ShlomovitzDepartment of Physics, University of Washington, Seattle, Washington; Department of Chemistry, University of Washington, Seattle, Washington.
Lutz MaibaumDepartment of Chemistry, University of Washington, Seattle, Washington.
M SchickDepartment of Physics, University of Washington, Seattle, Washington. Electronic address: schick@phys.washington.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We simulate a simple phenomenological model describing phase behavior in a multicomponent membrane, a model capable of producing macroscopic phase separation, modulated phases, and microemulsions, all of which have been discussed in terms of raft phenomena. We show that one effect of thermal fluctuations on the mean-field phase diagram is that it permits a direct transition between either one of the coexisting liquid phases to a microemulsion. This implies that one system exhibiting phase separation can be related to a similar system exhibiting the heterogeneities characteristic of a microemulsion. The two systems could differ in their average membrane composition or in the relative compositions of their exoplasmic and cytoplasmic leaves. The model provides a unified description of these raft-associated phenomena.

Indexed as

Models, MolecularEmulsionsMembrane MicrodomainsTemperatureEmulsions

Identifiers

PMID24806930
PMCPMC4017284

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.