Evidence map›Paper›PMID 24806917›Full record

ReviewBiophysical journal2014

Permeation redux: thermodynamics and kinetics of ion movement through potassium channels.

Richard Horn, Benoît Roux, Johan Åqvist

Abstract readReview
In one paragraph

Review in Biophysical journal, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. The Molecular Mechanism of Ion Selectivity in Nanopores.Molecules (Basel, Switzerland) · 2024
    Article
  2. Review
  3. Article
  4. Allosteric regulation of substrate channeling:Frontiers in molecular biosciences · 2022
    Review
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Richard HornDepartment of Molecular Physiology and Biophysics, Jefferson Medical College, Philadelphia, Pennsylvania. Electronic address: richardspikehorn@gmail.com.
Benoît RouxDepartment of Biochemistry and Molecular Biology, The University of Chicago, Chicago, Illinois.
Johan ÅqvistDepartment of Cell & Molecular Biology, Uppsala University, Biomedical Center, Uppsala, Sweden.

Funding

Computational Studies of Ion Channels - Resubmission 01R01GM062342 · NIGMS · WEILL MEDICAL COLLEGE OF CORNELL UNIV · PI ROUX, BENOIT · 2001 to 2022
$8.7M
NIGMS NIH HHS R01 GM062342
6 · The paper itself

Abstract

The fundamental biophysics underlying the selective movement of ions through ion channels was launched by George Eisenman in the 1960s, using glass electrodes. This minireview examines the insights from these early studies and the explosive progress made since then.

Indexed as

MovementIonsKineticsPermeabilityPotassium ChannelsThermodynamicsIonsPotassium Channels

Identifiers

PMID24806917
PMCPMC4017269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.