ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2014
A qualitative study investigating chemotherapy-induced nausea as a symptom cluster.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 39 citations in OpenAlex.
- Associations between gastrointestinal symptoms and coexisting symptoms amongst patients in a palliative care unit: a PCOC-based longitudinal study.BMC palliative care · 2026Article
- Redefining Chemotherapy-Related Headaches: From Pathobiology to Differential Diagnosis and Management.International journal of molecular sciences · 2025Review
- Article
- GIP receptor agonism blocks chemotherapy-induced nausea and vomiting.Molecular metabolism · 2023Article
- Symptom Cluster Experiences of Patients Operated for Oral Cancer: A Mixed Methods Study.Seminars in oncology nursing · 2023Article
- On a pathway to resigned acceptance: Patients' experiences of living with symptom clusters in oral cancer.European journal of oncology nursing : the official journal of European Oncology Nursing Society · 2023Article
- Emotions are associated with the genesis of visually induced motion sickness in virtual reality.Experimental brain research · 2022Article
- Chewing gum reduces visually induced motion sickness.Experimental brain research · 2022Article
- Psychological predictors of chemotherapy-induced nausea in women with breast cancer: Expectancies and perceived susceptibility.European journal of cancer care · 2021Article
- Olanzapine Administration Reduces Chemotherapy-Induced Nausea Behavior in Rats.Biological research for nursing · 2021Article
- Exploring the nausea experience among female patients with breast cancer; A pilot interview study.Technical innovations & patient support in radiation oncology · 2020Article
- Stability of symptom clusters and sentinel symptoms during the first two cycles of adjuvant chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2019Article
- Non-invasive High Frequency Median Nerve Stimulation Effectively Suppresses Olfactory Intensity Perception in Healthy Males.Frontiers in human neuroscience · 2018Article
- Risk factors for delayed chemotherapy-induced nausea and vomiting with low-emetic-risk chemotherapy: a prospective, observational, multicenter study.Cancer management and research · 2018Article
- Symptom clusters during palliative chemotherapy and their influence on functioning and quality of life.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
- Advancing Symptom Science Through Symptom Cluster Research: Expert Panel Proceedings and Recommendations.Journal of the National Cancer Institute · 2017Review
- Differential clinical pharmacology of rolapitant in delayed chemotherapy-induced nausea and vomiting (CINV).Drug design, development and therapy · 2017Review
- Analysis of Dietary Intake during Consecutive-Day Chemotherapy for Bone and Soft-Tissue Sarcomas.Frontiers in nutrition · 2017Article
- The kitchen as therapy: qualitative assessment of an integrative cuisine workshop for patients undergoing chemotherapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Article
- Identifying Severe Adverse Event Clusters Using the National Cancer Institute's Common Terminology Criteria for Adverse Events.Journal of oncology practice · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe prevention of chemotherapy-induced vomiting has been improved by antiemetics, but nausea remains problematic. This study explores the concept that this is partly because patients use the term nausea to describe a cluster of symptoms.
methodsA total of 42 cancer patients currently being treated (n = 21) or at least 6 months of past treatment (median 3.5 years; n = 21) with experience of chemotherapy-induced nausea consented to semi-structured interviews about nausea, which were transcribed and analysed. There were 24 females and 18 males.
resultsThe nature, number, location, duration and intensity of experiences described as nausea varied. Physical and psychological symptoms included dry retching, vomiting, anorexia, indigestion, change of taste, dizziness, bloating, reflux, inability to concentrate, fatigue and restlessness. Patients located nausea in sites ranging from the head/neck, sternum and mid and lower abdomen to the whole body. Some patients identified symptoms as part of the experience of nausea, and others described symptoms associated with nausea but separate from it. For most, distinguishing features of chemotherapy-induced (as opposed to other) nausea were its constant presence over time, fatigue and emotional associations with the cancer diagnosis. Triggers varied and included food (smells), negative emotions including anxiety, movement, smells (e.g., hand cream, cleaning products), treatment-related events, tooth brushing and mentioning nausea. Prescribed antiemetics were consistently noted as reducing the intensity of, but for many, not completely alleviating, nausea. Distraction and relaxation were preferred management techniques.
conclusionControl of nausea will require treating the particular cluster of symptoms which a patient is experiencing as nausea.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.