ArticleThe Journal of reproduction and development2014
Molecular cloning of rat and porcine retina-derived POU domain factor 1 (POU6F2) from a pituitary cDNA library.
Article in The Journal of reproduction and development, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 10 citations in OpenAlex.
- Article
- Utilizing image and caption information for biomedical document classification.Bioinformatics (Oxford, England) · 2021Article
- Identification of a novel somatic mutation of POU6F2 by whole-genome sequencing in prolactinoma.Molecular genetics & genomic medicine · 2019Article
- Restricted Presence of POU6F2 in Human Corneal Endothelial Cells Uncovered by Extension of the Promoter-level Expression Atlas.EBioMedicine · 2017Article
- Involvement of DNA methylation in regulating rat Prop1 gene expression during pituitary organogenesis.The Journal of reproduction and development · 2017Article
- Whole-Exome Sequencing of Salivary Gland Mucoepidermoid Carcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2017Article
- Identification of molecular signatures specific for distinct cranial sensory ganglia in the developing chick.Neural development · 2016Article
- Search for regulatory factors of the pituitary-specific transcription factor PROP1 gene.The Journal of reproduction and development · 2016Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Homeobox transcription factors are known to play crucial roles in the anterior lobe of the pituitary gland. During molecular cloning with the Yeast One-Hybrid System using a 5'-upstream region of the porcine Fshβ as a bait sequence, we have cloned a cDNA encoding a partial sequence of the retina-derived POU domain factor 1 (RPF1) from the porcine pituitary cDNA library and confirmed its specific binding to the bait sequence. In situ hybridization was performed to examine localization of Rpf1 and showed that this gene is expressed in the stem/progenitor cells of the rat pituitary primordium as well as the diencephalon and retina. In addition, real-time PCR demonstrated that Rpf1 transcripts are abundant in early embryonic periods but that this is followed by a decrease during pituitary development, indicating that this factor plays a role in differentiating cells of the pituitary. The transcriptional activity of RPF1 for genes of Prop1, Prrx1 and Prrx2, which were characterized as genes participating in the pituitary stem/progenitor cells by our group, was then examined with full-length cDNA obtained from the rat pituitary. RPF1 showed regulatory activity for Prop1 and Prrx2, but not for Prrx1. These results indicate the involvement of this retina-derived factor in pituitary development.
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Registered trials
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