Evidence map›Paper›PMID 24804260›Full record

ArticleBioMed research international2014

Predicting the types of J-proteins using clustered amino acids.

Pengmian Feng, Hao Lin, Wei Chen, Yongchun Zuo

Abstract read
In one paragraph

Article in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Research progress of reduced amino acid alphabets in protein analysis and prediction.Computational and structural biotechnology journal · 2022
    Review
  3. Article
  4. The expanding world of plant J-domain proteins.Critical reviews in plant sciences · 2019
    Article
  5. A Hybrid Classification System for Heart Disease Diagnosis Based on the RFRS Method.Computational and mathematical methods in medicine · 2017
    Article
  6. Article
  7. Identifying NMolecular genetics and genomics : MGG · 2016
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pengmian FengSchool of Public Health, Hebei United University, Tangshan 063000, China.
Hao LinKey Laboratory for Neuroinformation of Ministry of Education, Center of Bioinformatics, School of Life Science and Technology, University of Electronic Science and Technology of China, Chengdu 610054, China.ORCID 0000-0001-6265-2862
Wei ChenDepartment of Physics, School of Sciences, Center for Genomics and Computational Biology, Hebei United University, Tangshan 063000, China.ORCID 0000-0002-6857-7696
Yongchun ZuoThe National Research Center for Animal Transgenic Biotechnology, Inner Mongolia University, Hohhot 010021, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

J-proteins are molecular chaperones and present in a wide variety of organisms from prokaryote to eukaryote. Based on their domain organizations, J-proteins can be classified into 4 types, that is, Type I, Type II, Type III, and Type IV. Different types of J-proteins play distinct roles in influencing cancer properties and cell death. Thus, reliably annotating the types of J-proteins is essential to better understand their molecular functions. In the present work, a support vector machine based method was developed to identify the types of J-proteins using the tripeptide composition of reduced amino acid alphabet. In the jackknife cross-validation, the maximum overall accuracy of 94% was achieved on a stringent benchmark dataset. We also analyzed the amino acid compositions by using analysis of variance and found the distinct distributions of amino acids in each family of the J-proteins. To enhance the value of the practical applications of the proposed model, an online web server was developed and can be freely accessed.

Indexed as

Amino AcidsAmino Acid SequenceArtificial IntelligenceDatabases, ProteinHSP40 Heat-Shock ProteinsHumansMolecular ChaperonesSupport Vector MachineAmino AcidsHSP40 Heat-Shock ProteinsMolecular Chaperones

Identifiers

PMID24804260
PMCPMC3996952

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.