Evidence map›Paper›PMID 24804257›Full record

ReviewBioMed research international2014

SPECT- and PET-based approaches for noninvasive diagnosis of acute renal allograft rejection.

Helga Pawelski, Uta Schnöckel, Dominik Kentrup, Alexander Grabner, Michael Schäfers, Stefan Reuter

Abstract readReview
In one paragraph

Review in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Review
  3. The uptake of [Frontiers in transplantation · 2023
    Article
  4. Review
  5. Update on imaging-based diagnosis of acute renal allograft rejection.American journal of nuclear medicine and molecular imaging · 2019
    Review
  6. Article
  7. Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Helga PawelskiDepartment of Medicine D, Experimental Nephrology, University of Münster, Albert-Schweizer Campus 1, 48149 Münster, Germany.
Uta SchnöckelDepartment of Nuclear Medicine, University of Münster, Albert-Schweizer Campus 1, 48149 Münster, Germany.
Dominik KentrupDepartment of Medicine D, Experimental Nephrology, University of Münster, Albert-Schweizer Campus 1, 48149 Münster, Germany.
Alexander GrabnerDepartment of Medicine D, Experimental Nephrology, University of Münster, Albert-Schweizer Campus 1, 48149 Münster, Germany.
Michael SchäfersDepartment of Nuclear Medicine, University of Münster, Albert-Schweizer Campus 1, 48149 Münster, Germany ; European Institute for Molecular Imaging, University of Münster, Albert-Schweizer Campus 1, 48149 Münster, Germany.
Stefan ReuterDepartment of Medicine D, Experimental Nephrology, University of Münster, Albert-Schweizer Campus 1, 48149 Münster, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Molecular imaging techniques such as single photon emission computed tomography (SPECT) or positron emission tomography are promising tools for noninvasive diagnosis of acute allograft rejection (AR). Given the importance of renal transplantation and the limitation of available donors, detailed analysis of factors that affect transplant survival is important. Episodes of acute allograft rejection are a negative prognostic factor for long-term graft survival. Invasive core needle biopsies are still the "goldstandard" in rejection diagnostics. Nevertheless, they are cumbersome to the patient and carry the risk of significant graft injury. Notably, they cannot be performed on patients taking anticoagulant drugs. Therefore, a noninvasive tool assessing the whole organ for specific and fast detection of acute allograft rejection is desirable. We herein review SPECT- and PET-based approaches for noninvasive molecular imaging-based diagnostics of acute transplant rejection.

Indexed as

Positron-Emission TomographyTomography, Emission-Computed, Single-PhotonGraft RejectionHumansKidneyKidney TransplantationRadiographyTransplantation, Homologous

Identifiers

PMID24804257
PMCPMC3988725

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.