Evidence map›Paper›PMID 24804220›Full record

Trial reportBioMed research international2014

Resistance exercise with older fallers: its impact on intermuscular adipose tissue.

Janelle L Jacobs, Robin L Marcus, Glen Morrell, Paul LaStayo

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BioMed research international, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Intermuscular Adipose Tissue in CKD: A Window into Muscle Quality and Health?Clinical journal of the American Society of Nephrology : CJASN · 2025
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Effects of 10-week walking and walking with home-based resistance training on muscle quality, muscle size, and physical functional tests in healthy older individuals.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2018
    Article
  17. Review
  18. Chronic Eccentric Exercise and the Older Adult.Sports medicine (Auckland, N.Z.) · 2015
    Review
  19. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Janelle L JacobsDepartment of Physical Therapy, University of Utah, 520 Wakara Way, Salt Lake City, UT 84108, USA.
Robin L MarcusDepartment of Physical Therapy, University of Utah, 520 Wakara Way, Salt Lake City, UT 84108, USA.
Glen MorrellDepartment of Radiology, University of Utah, 30 N 1900 E, Salt Lake City, UT 84132, USA.
Paul LaStayoDepartment of Physical Therapy, University of Utah, 520 Wakara Way, Salt Lake City, UT 84108, USA.
University of Utah · US

Funding

Reducing Falls with RENEW in Older Individuals Who Have FallenR01AG031255 · NIA · UNIVERSITY OF UTAH · PI LASTAYO, PAUL C · 2008 to 2012
$2.2M
NIA NIH HHS R01 AG031255NIA NIH HHS R01AG031255
6 · The paper itself

Abstract

objectiveGreater skeletal muscle fat infiltration occurs with age and contributes to numerous negative health outcomes. The primary purpose was to determine whether intermuscular adipose tissue (IMAT) can be influenced by an exercise intervention and if a greater reduction in IMAT occurs with eccentric versus traditional resistance training.

methodsSeventy-seven older adults (age 75.5 ± 6.8) with multiple comorbidities and a history of falling completed a three-month exercise intervention paired with either eccentric or traditional resistance training. MRI of the mid-thigh was examined at three time points to determine changes in muscle composition after intervention.

resultsNo differences in IMAT were observed over time, and there were no differences in IMAT response between intervention groups. Participants in the traditional group lost a significant amount of lean tissue (P = 0.007) in the nine months after intervention, while participants in the eccentric group did not (P = 0.32). When IMAT levels were partitioned into high and low IMAT groups, there were differential IMAT responses to intervention with the high group lowering thigh IMAT.

conclusionsThere is no decrease in thigh IMAT after a three-month exercise intervention in older adults at risk for falling and no benefit to eccentric training over traditional resistance training for reducing IMAT in these individuals.

Indexed as

Adipose TissueExerciseMuscle, SkeletalAccidental FallsAgedAged, 80 and overFemaleHumansMaleRisk Factors

Identifiers

PMID24804220
PMCPMC3996328
OpenAlexW2064273648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.